QuickView for lipoprotein lipase (gene)

Gene Symbol:

LPL Homo sapiens

Full name:

lipoprotein lipase

Synonyms:

HDLCQ11, LIPD, lipoprotein lipase

Genomic Location:

Chr 8: 19840862-19869050

Description:

LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutation...

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LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  OCT1_05 ,  STAT4_01 ,  OCT1_B ,  OCT1_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  STAT6_01 ,  OCT1_Q5_01 ,  OCT_C ,  HNF4_01 ,  TATAAA_TATA_01 ,  OCT1_Q6 ,  CDX2_Q5 ,  CAGGTG_E12_Q6 ,  TATA_C ,  STAT5A_03 ,  PTF1BETA_Q6 ,  OCT1_02 ,  HAND1E47_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  PPAR_DR1_Q2 ,  ER_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-29

Cytogenetic Map:

8p21.3

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