QuickView for myogenin (gene)
- Gene Symbol:
- MYOG
Homo sapiens - Full name:
- myogenin
- Synonyms:
- MYF4, bHLHc3, myf-4, myogenin, class C basic helix-loop-helix protein 3, myogenic factor 4
- Genomic Location:
- Chr 1: 201318880-201322000
- Description:
-
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
1q32.1
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | chromatin binding | RNA polymerase II regulatory region DNA binding | E-box binding | DNA binding | sequence-specific double-stranded DNA binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | chromatin DNA binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | negative regulation of phosphorylation | positive regulation of striated muscle cell differentiation | regulation of myoblast fusion | regulation of muscle system process | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | response to cytokine | positive regulation of cellular component organization | muscle tissue development | positive regulation of ATP metabolic process | positive regulation of skeletal muscle tissue development | regulation of cell development | positive regulation of striated muscle tissue development | regulation of carbohydrate metabolic process | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | response to metal ion | cellular response to tumor necrosis factor | cell differentiation | striated muscle cell development | positive regulation of phosphate metabolic process | striated muscle atrophy | positive regulation of oxidative phosphorylation | positive regulation of cellular biosynthetic process | cellular process | regulation of glycolytic process | regulation of syncytium formation by plasma membrane fusion | developmental growth | myotube cell development | response to estradiol | regulation of skeletal muscle cell proliferation | regulation of striated muscle tissue development | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | regulation of oxidative phosphorylation | positive regulation of muscle cell differentiation | muscle structure development | muscle cell differentiation | skeletal muscle organ development | cellular response to retinoic acid | regulation of myotube differentiation | regeneration | regulation of cellular process | cellular response to lipid | regulation of skeletal muscle fiber development | regulation of metabolic process | organic cyclic compound metabolic process | regulation of skeletal muscle satellite cell proliferation | RNA biosynthetic process | cellular aromatic compound metabolic process | negative regulation of nucleotide metabolic process | response to gravity | response to muscle inactivity | cellular response to metal ion | response to stimulus | cellular response to lithium ion | muscle cell development | positive regulation of muscle atrophy | response to stress | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | cellular response to inorganic substance | cellular nitrogen compound metabolic process | positive regulation of myoblast differentiation | cellular response to organic cyclic compound | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | mRNA metabolic process | cellular biosynthetic process | muscle fiber development | regulation of nucleic acid-templated transcription | cellular response to magnetism | cellular response to hormone stimulus | regulation of skeletal muscle tissue development | response to inactivity | system development | nitrogen compound metabolic process | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of ATP metabolic process | response to activity | response to denervation involved in regulation of muscle adaptation | positive regulation of skeletal muscle fiber development | positive regulation of muscle organ development | regulation of phosphorylation | mRNA transcription by RNA polymerase II | wound healing | positive regulation of cell cycle | regulation of gene expression | response to lipid | cell cycle | regulation of cell cycle arrest | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of syncytium formation by plasma membrane fusion | regulation of transcription by RNA polymerase II | response to lithium ion | response to magnetism | positive regulation of cell differentiation | cellular response to cytokine stimulus | biosynthetic process | aromatic compound biosynthetic process | striated muscle tissue development | regulation of cellular metabolic process | skeletal muscle atrophy | mRNA transcription | regulation of RNA metabolic process | response to retinoic acid | striated muscle cell differentiation | positive regulation of cell cycle arrest | negative regulation of carbohydrate metabolic process | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | skeletal muscle adaptation | response to organic substance | response to wounding | anatomical structure development | metabolic process | positive regulation of cell development | cell fate commitment | regulation of RNA biosynthetic process | regulation of myoblast differentiation | response to electrical stimulus involved in regulation of muscle adaptation | positive regulation of myoblast fusion | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of glycolytic process | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | animal organ development | gene expression | muscle atrophy | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | regulation of striated muscle cell differentiation | negative regulation of ATP biosynthetic process | regulation of ATP metabolic process | regulation of phosphate metabolic process | muscle cell fate commitment | response to muscle activity involved in regulation of muscle adaptation | positive regulation of muscle tissue development | transcription, DNA-templated | skeletal muscle tissue regeneration | cellular response to estradiol stimulus | regulation of transcription, DNA-templated | myotube differentiation | response to organic cyclic compound | myoblast differentiation | cell development | positive regulation of phosphorylation | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | regulation of muscle cell differentiation | positive regulation of cell cycle process | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | response to electrical stimulus | regulation of generation of precursor metabolites and energy | positive regulation of metabolic process | ossification | cellular metabolic process | response to tumor necrosis factor | cellular response to organic substance | tissue regeneration | skeletal muscle cell differentiation | regulation of cellular component organization | muscle organ development | muscle system process | positive regulation of myotube differentiation | response to muscle activity | positive regulation of gene expression | skeletal muscle fiber development | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | transcription factor complex | intracellular organelle | protein-containing complex | protein-DNA complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
