QuickView for myosin-II (gene)

Gene Symbol:

MYH10 Homo sapiens

Full name:

myosin heavy chain 10

Synonyms:

NMMHC-IIB, NMMHCB, myosin-10, cellular myosin heavy chain, type B, myosin heavy chain, nonmuscle type B, myosin, heavy chain 10, non-muscle, myosin, heavy polypeptide 10, non-muscle, nonmuscle myosin II heavy chain-B, nonmuscle myosin heavy chain IIB

Genomic Location:

Chr 17: 8318255-8474761

Description:

This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been ...

View Full Description

This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene have been associated with May-Hegglin anomaly and developmental defects in brain and heart. Multiple transcript variants encoding different isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

STAT1_02 ,  TTANTCA_UNKNOWN ,  RYTTCCTG_ETS2_B ,  TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D ,  PPARA_01 ,  YTATTTTNR_MEF2_02 ,  E2F4DP1_01 ,  GCANCTGNY_MYOD_Q6 ,  CEBP_Q2_01 ,  CAGTGTT_MIR141_MIR200A ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  GATAAGR_GATA_C ,  SREBP1_Q6 ,  STAT1_03 ,  HNF4_DR1_Q3 ,  WTGAAAT_UNKNOWN ,  HNF4_01 ,  CDP_02 ,  E2F_Q6 ,  E2F1_Q6_01 ,  CAGGTG_E12_Q6 ,  DR1_Q3 ,  ETS2_B ,  AP2_Q6_01 ,  E2F_Q4 ,  TGCCTTA_MIR124A ,  GGGCGGR_SP1_Q6 ,  E2F1DP2_01 ,  LMO2COM_02 ,  YTTCCNNNGGAMR_UNKNOWN ,  E2F1DP1_01 ,  AREB6_03 ,  GFI1_01 ,  GTGCCTT_MIR506 ,  E2F1DP1RB_01 ,  AAAYRNCTG_UNKNOWN ,  E2F_02 ,  PAX5_01 ,  COUP_DR1_Q6 ,  TGCTTTG_MIR330 ,  E2F1_Q3 ,  E2F4DP2_01 ,  CTTTGT_LEF1_Q2 ,  CACBINDINGPROTEIN_Q6 ,  AACTTT_UNKNOWN ,  ACAWYAAAG_UNKNOWN ,  PPAR_DR1_Q2 ,  ETS1_B ,  RRCCGTTA_UNKNOWN ,  ACCATTT_MIR522 ,  HNF4_01_B ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-194 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-320 ,  Predicted Gene Targets for miR-330 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-409-3p ,  Predicted Gene Targets for miR-543

Cytogenetic Map:

17p13.1

search → result