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QuickView for nAChR;jsessionid=26C292270D3278B77081881CB3809F3D;jsessionid=6AA07BE99985712133F0B975BA6249DE;jsessionid=69946419E9D4655D3BF665173A5580F8;jsessionid=9A11D7E0C3C1B8FCA0B538E5FF6500FF;jsessionid=516121E48466E4F579466D88D7EE1285;jsessionid=0ECDBDE233B935970229D814AAE06D18 (gene)


Gene Symbol:
CHRNB3 Homo sapiens Homo sapiens
Full name:
cholinergic receptor nicotinic beta 3 subunit
Synonyms:
neuronal acetylcholine receptor subunit beta-3, acetylcholine receptor, neuronal nicotinic, beta-3 subunit, acetylcholine receptor, nicotinic, beta 3 (neuronal), cholinergic receptor, nicotinic beta 3, cholinergic receptor, nicotinic, beta 3 (neuronal), cholinergic receptor, nicotinic, beta polypeptide 3
Genomic Location:
Chr 8: 42671719-42711366
Description:
The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary struc...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8
8p11.21


Transcripts Names
NM_000749
NM_001347717
XM_011544390
Protein Names
Q05901
Q15827



GO Molecular Function

neurotransmitter receptor activity | cation binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | acetylcholine receptor activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | ion binding | acetylcholine binding | hormone binding | channel activity | drug binding | ion channel activity | substrate-specific channel activity

GO Biological Process

establishment of localization | excitatory postsynaptic potential | response to drug | cellular process | localization | passive transmembrane transporter activity | chemical synaptic transmission | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | response to stimulus | ion gated channel activity | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of membrane potential | response to nicotine | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | response to toxic substance | cell communication | neuromuscular synaptic transmission | cell surface receptor signaling pathway | transmembrane transport | signaling | channel activity | synaptic transmission, cholinergic | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | synapse | neuron projection | cell | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | receptor complex | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | integral component of plasma membrane | cell periphery | transmembrane transporter complex | ion channel complex | cell junction | acetylcholine-gated channel complex | membrane | intrinsic component of plasma membrane