QuickView for organic cation transporter 1 (gene)

Gene Symbol:

SLC22A1 Homo sapiens

Full name:

solute carrier family 22 member 1

Synonyms:

HOCT1, OCT1, oct1_cds, solute carrier family 22 member 1, organic cation transporter 1, solute carrier family 22 (organic cation transporter), member 1

Genomic Location:

Chr 6: 160462853-160499740

Description:

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twel...

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Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGNNNNNNKCCAR_UNKNOWN

Cytogenetic Map:

6q25.3

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