QuickView for orphanin FQ (gene)
- Gene Symbol:
- PNOC
Homo sapiens - Full name:
- prepronociceptin
- Synonyms:
- N/OFQ, NOP, OFQ, PPNOC, ppN/OFQ, prepronociceptin, nociceptin, nocistatin, orphanin FQ, pre-pro-N/OFQ, pronociceptin
- Genomic Location:
- Chr 8: 28230568-28256787
- Description:
-
This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include nociceptin, nocistatin, and orphanin FQ2 (OFQ2). Nociceptin, also known as orphanin FQ, is a 17-amino acid neuropeptide that binds to the nociceptin receptor to induce increased pain sensitivity, and may additionally reg...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
8p21.1
GO Molecular Function
signaling receptor binding | hormone activity | molecular function regulator | opioid peptide activity | protein binding | receptor regulator activity | neuropeptide hormone activity | receptor ligand activity
GO Biological Process
cellular process | neuropeptide signaling pathway | chemical synaptic transmission | female pregnancy | regulation of cellular process | response to stimulus | reproduction | hormone activity | G-protein coupled receptor signaling pathway | cell-cell signaling | molecular function regulator | reproductive process | regulation of signal transduction | nervous system process | synaptic signaling | cell communication | opioid peptide activity | regulation of signaling receptor activity | receptor regulator activity | neuropeptide hormone activity | receptor ligand activity | sensory perception | regulation of cell communication | signaling | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
dendrite | synapse | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | distal axon | dendritic tree | presynapse | cell projection | plasma membrane | extracellular region | axon terminus | cell periphery | axon | neuron projection terminus | membrane
