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QuickView for p65 (gene)


Gene Symbol:
Syt1 Rattus norvegicus Rattus norvegicus
Full name:
synaptotagmin 1
Synonyms:
P65, synaptotagmin-1, synaptotagmin I, sytI
Genomic Location:
Chr 7: 47240796-47795679
Description:
integral component of synaptic vesicle membranes; important for exocytosis and vesicle trafficking to the active zone of synapses; may be the calcium sensor for calcium-dependent exocytosis
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Macaca mulatta Bos taurus Gallus gallus Danio rerio Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Predicted Gene Targets for let-7 Predicted Gene Targets for miR-1 Predicted Gene Targets for miR-128 Predicted Gene Targets for miR-129 Predicted Gene Targets for miR-133 Predicted Gene Targets for miR-135 Predicted Gene Targets for miR-146 Predicted Gene Targets for miR-148 Predicted Gene Targets for miR-153 Predicted Gene Targets for miR-19


Protein Names
P21707
Q707P5
Q707P0
Q3S2E6



GO Molecular Function

low-density lipoprotein particle receptor binding | phosphatidylinositol-4,5-bisphosphate binding | modified amino acid binding | cation binding | clathrin binding | lipoprotein particle receptor binding | syntaxin binding | lipid binding | signaling receptor binding | phospholipid binding | anion binding | phosphatidylinositol bisphosphate binding | calcium-dependent protein binding | identical protein binding | protein heterodimerization activity | ion binding | protein binding | protein homodimerization activity | phosphatidylserine binding | protein dimerization activity | phosphatidylinositol binding | syntaxin-3 binding | SNARE binding | calcium ion binding | calmodulin binding | calcium-dependent phospholipid binding | syntaxin-1 binding | metal ion binding | protein C-terminus binding | phosphatidylinositol phosphate binding

GO Biological Process

synaptic vesicle exocytosis | brain development | protein homooligomerization | exocytosis | detection of stimulus | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | neurotransmitter secretion | regulation of cell development | regulation of localization | establishment of localization | positive regulation of developmental process | response to metal ion | cell differentiation | fast, calcium ion-dependent exocytosis of neurotransmitter | nervous system development | neurogenesis | regulation of organelle organization | generation of neurons | intracellular transport | cellular process | secretion | regulation of catecholamine secretion | establishment of organelle localization | localization | positive regulation of synaptic transmission | chemical synaptic transmission | membrane docking | regulation of neuron projection development | response to inorganic substance | establishment of localization in cell | regulation of cell differentiation | regulation of cellular process | positive regulation of cell growth | positive regulation of vesicle fusion | organelle localization | cellular component organization | cellular response to metal ion | head development | response to stimulus | regulation of response to drug | regulation of dendrite extension | cellular response to inorganic substance | cellular localization | secretion by cell | cellular component assembly | modulation of chemical synaptic transmission | cell-cell signaling | positive regulation of exocytosis | regulation of neurotransmitter levels | synaptic vesicle cycle | system development | positive regulation of organelle organization | detection of chemical stimulus | positive regulation of neuron projection development | multicellular organism development | regulation of synaptic transmission, glutamatergic | detection of calcium ion | protein complex oligomerization | synaptic vesicle recycling | regulation of neuron differentiation | positive regulation of secretion | synaptic signaling | positive regulation of cell projection organization | vesicle-mediated transport | positive regulation of cell differentiation | establishment of vesicle localization | regulated exocytosis | positive regulation of regulated secretory pathway | cell communication | synaptic vesicle endocytosis | positive regulation of transport | regulation of vesicle fusion | regulation of dopamine secretion | protein-containing complex assembly | regulation of growth | cellular response to calcium ion | import into cell | regulation of exocytosis | anatomical structure development | positive regulation of neurogenesis | positive regulation of cell development | positive regulation of calcium ion-dependent exocytosis | regulation of vesicle-mediated transport | calcium ion regulated exocytosis | endocytosis | regulation of secretion | animal organ development | vesicle docking | regulation of regulated secretory pathway | calcium ion-regulated exocytosis of neurotransmitter | regulation of cell communication | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of developmental growth | synaptic vesicle localization | protein heterooligomerization | regulation of nervous system development | regulation of developmental process | regulation of ion transport | developmental process | regulation of cell growth | regulation of transport | neurotransmitter transport | signal release | positive regulation of dendrite extension | regulation of calcium ion-dependent exocytosis | response to calcium ion | central nervous system development | vesicle localization | positive regulation of neuron differentiation | regulation of cell projection organization | synaptic vesicle transport | regulation of cellular component organization | positive regulation of signaling | regulation of signaling | multicellular organismal process

GO Cellular Component

presynaptic membrane | secretory granule | chromaffin granule | integral component of organelle membrane | exocytic vesicle | integral component of membrane | intracellular membrane-bounded organelle | synapse | neuron projection | organelle membrane | cytoplasmic vesicle | cell | distal axon | chromaffin granule membrane | intrinsic component of membrane | synaptic membrane | terminal bouton | transport vesicle membrane | cytoplasm | intracellular organelle | secretory granule membrane | presynapse | Golgi apparatus | protein-containing complex | cell projection | secretory vesicle | endomembrane system | plasma membrane | exocytic vesicle membrane | vesicle | transport vesicle | dense core granule | SNARE complex | synaptic vesicle | membrane-bounded organelle | organelle | vesicle membrane | axon terminus | cell periphery | excitatory synapse | axon | neuron projection terminus | synaptic vesicle membrane | intracellular vesicle | integral component of synaptic vesicle membrane | intracellular | cell junction | membrane | cytoplasmic vesicle membrane