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QuickView for p73 (gene)


Gene Symbol:
Tp73 Rattus norvegicus Rattus norvegicus
Full name:
tumor protein p73
Synonyms:
P73, Trp73, tumor protein p73, transformation related protein 73
Genomic Location:
Chr 5: 170851670-170878915
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Bos taurus
External Links:
Entrez Gene


Transcripts Names
XM_342992
XM_001077013
NM_001108696
Protein Names
D4AA88



GO Molecular Function

sequence-specific DNA binding | kinase binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | protein kinase binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | p53 binding | DNA binding | MDM2/MDM4 family protein binding | sequence-specific double-stranded DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | regulation of JUN kinase activity | negative regulation of JNK cascade | negative regulation of phosphorylation | brain development | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | negative regulation of MAPK cascade | release of cytochrome c from mitochondria | regulation of neurogenesis | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | regulation of programmed cell death | hippocampus development | establishment of localization | negative regulation of neuron death | negative regulation of cellular process | negative regulation of kinase activity | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | regulation of MAP kinase activity | regulation of heart growth | cell differentiation | positive regulation of intrinsic apoptotic signaling pathway | defense response | negative regulation of organ growth | nervous system development | intrinsic apoptotic signaling pathway in response to DNA damage | response to drug | negative regulation of protein phosphorylation | neurogenesis | positive regulation of phosphate metabolic process | generation of neurons | regulation of cardiac muscle cell proliferation | regulation of neuron death | negative regulation of stress-activated protein kinase signaling cascade | positive regulation of cellular biosynthetic process | cellular process | secretion | positive regulation of signal transduction by p53 class mediator | negative regulation of muscle organ development | localization | negative regulation of signaling | neuron development | negative regulation of developmental growth | regulation of striated muscle tissue development | positive regulation of protein kinase activity | negative regulation of apoptotic process | digestive tract morphogenesis | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cell differentiation | intrinsic apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | positive regulation of response to DNA damage stimulus | urogenital system development | head development | negative regulation of cardiac muscle tissue development | response to stimulus | positive regulation of protein metabolic process | response to stress | negative regulation of protein kinase activity | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | programmed cell death | cellular nitrogen compound metabolic process | apoptotic mitochondrial changes | positive regulation of gliogenesis | negative regulation of muscle tissue development | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | regulation of cellular component size | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | cellular component assembly | cellular biosynthetic process | kidney development | mitochondrion organization | regulation of oligodendrocyte differentiation | activation of protein kinase activity | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to nitrogen compound | negative regulation of neuron apoptotic process | apoptotic process | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of growth | negative regulation of phosphate metabolic process | multicellular organism development | negative regulation of catalytic activity | regulation of MAPK cascade | cellular response to DNA damage stimulus | protein complex oligomerization | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | telencephalon development | positive regulation of cell cycle | regulation of neuron differentiation | regulation of gene expression | cellular response to stress | cell cycle | regulation of signal transduction by p53 class mediator | regulation of cell cycle arrest | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | negative regulation of protein serine/threonine kinase activity | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | digestive tract development | negative regulation of stress-activated MAPK cascade | protein tetramerization | regulation of apoptotic signaling pathway | post-embryonic development | negative regulation of cardiac muscle cell proliferation | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of neuron apoptotic process | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | negative regulation of striated muscle tissue development | limbic system development | regulation of protein phosphorylation | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | negative regulation of MAP kinase activity | regulation of RNA metabolic process | renal system development | regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | apoptotic signaling pathway | regulation of mitotic cell cycle | positive regulation of molecular function | positive regulation of cell cycle arrest | neuron differentiation | activation of MAPK activity | protein-containing complex assembly | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | positive regulation of protein modification process | regulation of growth | response to organic substance | positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator | regulation of cardiac muscle tissue development | digestive system development | cell cycle arrest | regulation of kinase activity | negative regulation of JUN kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | positive regulation of neurogenesis | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | metabolic process | positive regulation of cell development | regulation of RNA biosynthetic process | regulation of body fluid levels | negative regulation of programmed cell death | positive regulation of glial cell differentiation | positive regulation of cell death | body fluid secretion | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | cell death | animal organ development | forebrain development | negative regulation of neuron differentiation | pallium development | negative regulation of cellular protein metabolic process | gene expression | positive regulation of programmed cell death | positive regulation of kinase activity | regulation of phosphate metabolic process | intrinsic apoptotic signaling pathway by p53 class mediator | transcription, DNA-templated | cerebrospinal fluid secretion | regulation of JNK cascade | positive regulation of MAPK cascade | negative regulation of cell cycle | negative regulation of protein metabolic process | regulation of glial cell differentiation | regulation of stress-activated MAPK cascade | regulation of cell communication | regulation of gliogenesis | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | cell development | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage | regulation of developmental growth | positive regulation of phosphorylation | regulation of cell size | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of MAP kinase activity | regulation of organ growth | regulation of nervous system development | regulation of developmental process | regulation of intrinsic apoptotic signaling pathway by p53 class mediator | developmental process | organelle organization | positive regulation of cell cycle process | positive regulation of cell size | positive regulation of oligodendrocyte differentiation | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | positive regulation of metabolic process | cellular metabolic process | regulation of cell death | signal transduction by p53 class mediator | negative regulation of cell death | negative regulation of cell development | negative regulation of cell differentiation | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | regulation of muscle organ development | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | cytoplasm | intracellular organelle | Golgi apparatus | endomembrane system | nucleoplasm | chromatin | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular | cell junction