QuickView for p75 neurotrophin receptor (gene)
- Gene Symbol:
- Ngfr
Mus musculus - Full name:
- nerve growth factor receptor (TNFR superfamily, member 16)
- Synonyms:
- LNGFR, Tnfrsf16, p75, p75NGFR, p75NTR, tumor necrosis factor receptor superfamily member 16, NGF receptor, low affinity neurotrophin receptor p75NTR, low-affinity nerve growth factor receptor, p75 neurotrophin receptor
- Genomic Location:
- Chr 11: 95430132-95449012
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
nerve growth factor binding | neurotrophin binding | GTPase binding | peptide binding | amyloid-beta binding | coreceptor activity | transmembrane signaling receptor activity | enzyme binding | preprotein binding | signaling receptor binding | cytokine receptor binding | Ras GTPase binding | growth factor binding | ubiquitin-like protein ligase binding | neurotrophin receptor binding | neurotrophin TRKA receptor binding | death receptor activity | amide binding | signaling receptor activity | identical protein binding | protein binding | protein homodimerization activity | ubiquitin protein ligase binding | protein dimerization activity | small GTPase binding | Rab GTPase binding | calmodulin binding
GO Biological Process
molting cycle | cell morphogenesis | positive regulation of macromolecule biosynthetic process | regulation of cysteine-type endopeptidase activity | positive regulation of Ras protein signal transduction | detection of stimulus | epidermis morphogenesis | positive regulation of cellular component organization | regulation of neurogenesis | neuron projection morphogenesis | regulation of cellular localization | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | regulation of localization | morphogenesis of an epithelium | regulation of programmed cell death | establishment of localization | negative regulation of hair follicle development | neuron death | negative regulation of neuron death | dorsal aorta development | negative regulation of cellular process | positive regulation of developmental process | negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | cell differentiation | positive regulation of fibroblast proliferation | negative regulation of dendrite development | nervous system development | regulation of sprouting angiogenesis | cell part morphogenesis | neurogenesis | glucose homeostasis | positive regulation of phosphate metabolic process | generation of neurons | intracellular transport | regulation of neuron death | positive regulation of neurological system process | positive regulation of cellular biosynthetic process | cellular process | regulation of glucose import | circadian regulation of gene expression | localization | cell projection morphogenesis | positive regulation of synaptic transmission | protein transport | regulation of mitochondrial membrane potential | negative regulation of signaling | neuron development | macromolecule localization | negative regulation of apoptotic process | axon guidance | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | establishment of localization in cell | tissue development | regulation of neurological system process | regulation of cell differentiation | regulation of angiogenesis | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of odontogenesis of dentin-containing tooth | negative regulation of fibroblast growth factor receptor signaling pathway | small GTPase mediated signal transduction | positive regulation of cellular protein metabolic process | epithelium development | cellular response to organonitrogen compound | regulation of mitochondrial depolarization | cellular component organization | positive regulation of myelination | regulation of vasculature development | response to stimulus | vasculature development | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | neuron projection guidance | intracellular protein transport | positive regulation of cellular protein localization | regulation of cell proliferation | negative regulation of neuron projection development | negative regulation of angiogenesis | response to peptide | positive regulation of cysteine-type endopeptidase activity | circadian rhythm | programmed cell death | cellular localization | cardiovascular system development | response to temperature stimulus | rhythmic process | positive regulation of proteolysis | positive regulation of RNA biosynthetic process | regulation of odontogenesis | modulation of chemical synaptic transmission | positive regulation of synaptic transmission, glutamatergic | blood vessel development | regulation of nucleic acid-templated transcription | regulation of membrane potential | detection of abiotic stimulus | locomotion | response to nitrogen compound | negative regulation of neuron apoptotic process | apoptotic process | system development | regulation of signal transduction | modulation of excitatory postsynaptic potential | positive regulation of neuron projection development | regulation of synaptic transmission, cholinergic | multicellular organism development | regulation of synaptic transmission, glutamatergic | regulation of peptidase activity | negative regulation of dendritic spine development | regulation of MAPK cascade | positive regulation of protein kinase B signaling | regulation of catalytic activity | cellular response to oxidative stress | regulation of phosphorylation | hair follicle morphogenesis | artery development | regulation of small GTPase mediated signal transduction | regulation of neuron differentiation | regulation of gene expression | axon development | negative regulation of hair cycle | organic substance transport | cellular response to stress | nervous system process | cellular response to peptide | regulation of epidermis development | death receptor activity | regulation of glucose import in response to insulin stimulus | regulation of fibroblast growth factor receptor signaling pathway | regulation of membrane depolarization | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of pri-miRNA transcription by RNA polymerase II | regulation of protein localization to nucleus | regulation of myelination | positive regulation of Rho protein signal transduction | regulation of nitrogen compound metabolic process | neuron apoptotic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of cell projection organization | peptide transport | negative regulation of cellular response to growth factor stimulus | positive regulation of intracellular signal transduction | regulation of hair follicle development | regulation of transcription by RNA polymerase II | response to oxidative stress | axonogenesis | positive regulation of hydrolase activity | positive regulation of cell differentiation | regulation of Rho protein signal transduction | positive regulation of protein localization to nucleus | sensory perception of pain | regulation of cellular protein metabolic process | positive regulation of pri-miRNA transcription by RNA polymerase II | positive regulation of endopeptidase activity | positive regulation of odontogenesis | positive regulation of neuron death | epidermis development | regulation of apoptotic signaling pathway | skin development | cell morphogenesis involved in differentiation | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | cell communication | regulation of cellular metabolic process | regulation of neuron apoptotic process | cellular response to amyloid-beta | regulation of protein metabolic process | positive regulation of signal transduction | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | negative regulation of sprouting angiogenesis | regulation of cellular response to growth factor stimulus | positive regulation of molecular function | neuron differentiation | negative regulation of mitochondrial depolarization | negative regulation of epithelial cell proliferation | regulation of fibroblast proliferation | positive regulation of protein modification process | hair cycle | response to organic substance | negative regulation of cell projection organization | tissue morphogenesis | Rho protein signal transduction | response to wounding | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | anatomical structure development | positive regulation of neurogenesis | aorta development | positive regulation of small GTPase mediated signal transduction | regulation of neural precursor cell proliferation | cell projection organization | positive regulation of cell development | activation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | cellular protein localization | amide transport | hair cycle process | negative regulation of endothelial cell proliferation | chemical homeostasis | positive regulation of cell death | neuron projection development | cell death | regulation of glucose transmembrane transport | animal organ development | regulation of endothelial cell proliferation | negative regulation of neuron differentiation | nerve development | positive regulation of programmed cell death | ion homeostasis | regulation of cellular response to insulin stimulus | skin epidermis development | regulation of phosphate metabolic process | positive regulation of synaptic transmission, cholinergic | establishment of protein localization | positive regulation of odontogenesis of dentin-containing tooth | positive regulation of MAPK cascade | positive regulation of excitatory postsynaptic potential | regulation of dendrite development | sensory perception | regulation of cell communication | negative regulation of signal transduction | regulation of dendritic spine development | signaling | response to amyloid-beta | regulation of transcription, DNA-templated | cell development | protein localization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | regulation of Ras protein signal transduction | anatomical structure morphogenesis | regulation of endopeptidase activity | cellular macromolecule localization | regulation of nervous system development | regulation of developmental process | positive regulation of neural precursor cell proliferation | developmental process | detection of temperature stimulus | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | negative regulation of cell proliferation | regulation of hair cycle | negative regulation of vasculature development | Ras protein signal transduction | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | central nervous system development | positive regulation of metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | cellular response to organic substance | regulation of protein localization | regulation of cell death | negative regulation of cell death | negative regulation of cell development | circulatory system development | carbohydrate homeostasis | chemotaxis | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | hair follicle development | signal transduction | regulation of signaling | positive regulation of gene expression | negative regulation of neurogenesis | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cell projection membrane | clathrin-coated vesicle | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | external side of plasma membrane | cytoplasm | clathrin-coated endocytic vesicle | intracellular organelle | endoplasmic reticulum | membrane microdomain | dendritic tree | leading edge membrane | cell-cell junction | Golgi apparatus | cell projection | endomembrane system | postsynapse | plasma membrane | nuclear envelope | perikaryon | cell leading edge | membrane raft | vesicle | neuronal cell body membrane | postsynaptic density | asymmetric synapse | mitochondrion | dendrite membrane | membrane-bounded organelle | nucleus | organelle | postsynaptic specialization | cell periphery | cell body membrane | rough endoplasmic reticulum | intracellular vesicle | cell surface | endocytic vesicle | intracellular | cell junction | membrane | neuron projection membrane | coated vesicle
