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QuickView for p80 katanin (gene)


Gene Symbol:
KATNB1 Homo sapiens Homo sapiens
Full name:
katanin regulatory subunit B1
Synonyms:
KAT, LIS6, katanin p80 WD40 repeat-containing subunit B1, katanin (80 kDa), katanin p80 (WD repeat containing) subunit B 1, katanin p80 (WD40-containing) subunit B 1, katanin p80 WD40-containing subunit B1, katanin p80 subunit B1, p80 katanin
Genomic Location:
Chr 16: 56327161-56348663
Description:
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 16
16q21





GO Molecular Function

protein-containing complex binding | hydrolase activity | ATPase activity | pyrophosphatase activity | catalytic activity | cytoskeletal protein binding | nucleoside-triphosphatase activity | ATPase activity, coupled | dynein complex binding | protein heterodimerization activity | protein binding | protein dimerization activity | hydrolase activity, acting on acid anhydrides | microtubule binding | microtubule-severing ATPase activity | tubulin binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO Biological Process

regulation of supramolecular fiber organization | regulation of microtubule polymerization or depolymerization | positive regulation of cellular component organization | regulation of neurogenesis | regulation of cell development | negative regulation of protein complex disassembly | establishment of localization | negative regulation of cellular process | positive regulation of developmental process | microtubule cytoskeleton organization | cell differentiation | nervous system development | neurogenesis | regulation of organelle organization | generation of neurons | intracellular transport | microtubule-based process | cellular process | localization | protein transport | negative regulation of microtubule polymerization or depolymerization | macromolecule localization | regulation of neuron projection development | establishment of localization in cell | regulation of cell differentiation | regulation of cellular process | positive regulation of protein complex disassembly | cellular component organization | regulation of microtubule depolymerization | intracellular protein transport | supramolecular fiber organization | cellular localization | system development | positive regulation of organelle organization | positive regulation of neuron projection development | multicellular organism development | regulation of protein complex disassembly | regulation of neuron differentiation | organic substance transport | cell cycle | positive regulation of cell projection organization | peptide transport | positive regulation of protein depolymerization | positive regulation of cell differentiation | cell division | microtubule depolymerization | negative regulation of microtubule depolymerization | positive regulation of cytoskeleton organization | cellular protein complex disassembly | regulation of protein depolymerization | microtubule severing | regulation of microtubule-based process | anatomical structure development | positive regulation of neurogenesis | positive regulation of cell development | positive regulation of supramolecular fiber organization | negative regulation of cytoskeleton organization | cellular protein localization | amide transport | positive regulation of cell death | cytoskeleton organization | protein depolymerization | establishment of protein localization | microtubule polymerization or depolymerization | microtubule-severing ATPase activity | protein localization | protein-containing complex disassembly | cellular macromolecule localization | regulation of nervous system development | regulation of developmental process | developmental process | organelle organization | negative regulation of supramolecular fiber organization | positive regulation of microtubule depolymerization | positive regulation of neuron differentiation | protein targeting | regulation of cell projection organization | regulation of cell death | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | regulation of cytoskeleton organization | multicellular organismal process

GO Cellular Component

supramolecular fiber | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | microtubule associated complex | microtubule organizing center | cell body | cell | neuronal cell body | distal axon | microtubule | cytoplasm | spindle | intracellular organelle | centrosome | protein-containing complex | cell projection | plasma membrane | midbody | microtubule cytoskeleton | site of polarized growth | spindle pole | katanin complex | membrane-bounded organelle | nucleus | organelle | cell periphery | axon | growth cone | cytosol | cytoskeleton | intracellular | membrane | supramolecular complex