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QuickView for pea;jsessionid=96D5E6046831E00540056104CCFC7326;jsessionid=AE9F2C36B2DCFC8E2D20A0F7DC687644 (gene)

Gene Symbol:
DHX8 Homo sapiens Homo sapiens
Full name:
DEAH-box helicase 8
DDX8, Dhr2, HRH1, PRP22, PRPF22, ATP-dependent RNA helicase DHX8, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 8 (RNA helicase), DEAH (Asp-Glu-Ala-His) box polypeptide 8, DEAH box protein 8, RNA helicase HRH1
Genomic Location:
Chr 17: 38916860-38957206
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may b...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Gallus gallus Canis lupus familiaris Bos taurus Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 17

GO Molecular Function

ATP-dependent RNA helicase activity | 3'-5' RNA helicase activity | RNA-dependent ATPase activity | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP-dependent 3'-5' RNA helicase activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | identical protein binding | ATP-dependent helicase activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | RNA helicase activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | helicase activity | drug binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | RNA binding

GO Biological Process

RNA metabolic process | RNA processing | cellular process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | RNA splicing | RNA splicing, via transesterification reactions | cellular nitrogen compound metabolic process | mRNA metabolic process | nitrogen compound metabolic process | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | gene expression | protein-containing complex disassembly | heterocycle metabolic process | spliceosomal complex disassembly | cellular metabolic process | mRNA processing | mRNA splicing, via spliceosome | macromolecule metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | catalytic complex | catalytic step 2 spliceosome | cell | nuclear lumen | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | U2-type spliceosomal complex | ribonucleoprotein complex | spliceosomal complex | membrane-bounded organelle | nucleus | organelle | U2-type catalytic step 2 spliceosome | membrane-enclosed lumen | intracellular