QuickView for perforin (compound)

Name:	Perforin
Description:	A calcium-dependent pore-forming protein synthesized in cytolytic LYMPHOCYTES and sequestered in secretory granules. Upon immunological reaction between a cytolytic lymphocyte and a target cell, perforin is released at the plasma membrane and polymerizes into transmembrane tubules (forming pores) which lead to death of a target cell.
Synonyms:	Lymphocyte Pore Forming Protein; Cytolysin; Perforin 1; Pore-Forming Protein, Lymphocyte; Lymphocyte Pore-Forming Protein