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QuickView for phencyclidine (compound)
PubChem
| Name: | Phencyclidine |
|---|---|
| PubChem Compound ID: | 13727 |
| Description: | A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. |
| Molecular formula: | C17H26ClN |
| Molecular weight: | 279.848 g/mol |
| Synonyms: |
1-(1-Phenylcyclohexyl)piperidine hydrochloride; Phencyclidine hydrochloride [USAN]; PCP hydrochloride; Sernyl; GP-121; PHENYLCYCLINE HYDROCHLORIDE; Sernylan; 956-90-1; C.I. 395; NSC-40902.
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DrugBank
Identification
| Name: | Phencyclidine |
|---|---|
| Name (isomeric): | DB03575 |
| Drug Type: | small molecule |
| Description: | A hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to KETAMINE in structure and in many of its effects. Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (RECEPTORS, N-METHYL-D-ASPARTATE). As a drug of abuse, it is known as PCP and Angel Dust. |
| Synonyms: |
1-(1-Phenylcyclohexyl)piperidine hydrochloride; Magic mist; Whack; Zombie dust; Busy bee; Sernylan; Fenciclidina [inn-spanish]; Rocket fuel; CJS; Phencyclidinum [inn-latin].
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| Category: | Hallucinogens, Enzyme Inhibitors, Excitatory Amino Acid Antagonists |
| CAS number: | 77-10-1 |
Pharmacology
| Pharmacology: | Phencyclidine works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA Receptor. |
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| Mechanism of Action: |
The N-methyl-D-Aspartate (NMDA) receptor, a type of ionotropic receptor, is found on the dendrites of neurons and receives signals in the form of neurotransmitters. It is a major excitatory receptor in the brain. Normal physiological function requires that the activated receptor fluxes positive ions through the channel part of the receptor. PCP ent...
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| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
Enzymes
