QuickView for phosphoinositide 5-phosphatase (gene)

Gene Symbol:

Inpp5b Mus musculus

Full name:

inositol polyphosphate-5-phosphatase B

Synonyms:

5PTase, AW260155, INPP5P, type II inositol 1,4,5-trisphosphate 5-phosphatase, inositol polyphosphate-5-phosphatase, 75 kDa, phosphoinositide 5-phosphatase

Genomic Location:

Chr 4: 124419122-124478755

Description:

This gene encodes a member of the inositol polyphosphate-5-phosphatase (INPP5) family. This protein hydrolyzes the 5' phosphate from phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol-1,4,5-trisphosphate, which results in changes to multiple signaling pathways. This protein may be involved in protein trafficking and secretion. Homozygou...

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This gene encodes a member of the inositol polyphosphate-5-phosphatase (INPP5) family. This protein hydrolyzes the 5' phosphate from phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol-1,4,5-trisphosphate, which results in changes to multiple signaling pathways. This protein may be involved in protein trafficking and secretion. Homozygous knockout mice exhibit impaired spermatogenesis and male sterility. Alternative splicing of this gene results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  C. elegans ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CTGAGCC_MIR24 ,  AACTGAC_MIR223

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-223 ,  Predicted Gene Targets for miR-24

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