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QuickView for protein kinase CK2 (gene)


Gene Symbol:
CSNK2A1 Homo sapiens Homo sapiens
Full name:
casein kinase 2 alpha 1
Synonyms:
CK2A1, CKII, CSNK2A3, Cka1, Cka2, OCNDS, casein kinase II subunit alpha, CK II alpha 3, CK2 catalytic subunit alpha, casein kinase 2, alpha 1 polypeptide, casein kinase II alpha 1 polypeptide pseudogene, casein kinase II alpha 1 subunit, protein kinase CK2
Genomic Location:
Chr 20: 411338-472482
Description:
Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the cata...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 20
20p13





GO Molecular Function

ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | ATP binding | protein N-terminus binding | anion binding | adenyl nucleotide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | Hsp90 protein binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heat shock protein binding | heterocyclic compound binding | small molecule binding

GO Biological Process

RNA metabolic process | regulation of cell cycle process | regulation of cysteine-type endopeptidase activity | regulation of programmed cell death | peptidyl-amino acid modification | negative regulation of cysteine-type endopeptidase activity | negative regulation of cellular process | positive regulation of protein catabolic process | negative regulation of proteolysis | regulation of chromosome segregation | cellular process | negative regulation of ubiquitin-dependent protein catabolic process | chaperone-mediated protein folding | negative regulation of signaling | regulation of chromosome separation | negative regulation of apoptotic process | regulation of proteolysis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | negative regulation of apoptotic signaling pathway | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | negative regulation of cellular protein catabolic process | response to stimulus | peptidyl-threonine phosphorylation | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | protein serine/threonine kinase activity | programmed cell death | rhythmic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | protein modification process | cellular biosynthetic process | macromolecule modification | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | apoptotic process | nitrogen compound metabolic process | regulation of signal transduction | Wnt signaling pathway | negative regulation of catalytic activity | regulation of peptidase activity | phosphorus metabolic process | regulation of catalytic activity | negative regulation of peptidase activity | regulation of gene expression | cell cycle | regulation of signal transduction by p53 class mediator | regulation of nitrogen compound metabolic process | regulation of cysteine-type endopeptidase activity involved in apoptotic process | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | regulation of apoptotic signaling pathway | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of RNA metabolic process | protein metabolic process | regulation of growth | regulation of intracellular signal transduction | cell surface receptor signaling pathway | metabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | protein folding | cell death | negative regulation of cellular protein metabolic process | gene expression | regulation of Wnt signaling pathway | transcription, DNA-templated | negative regulation of protein catabolic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | positive regulation of growth | regulation of transcription, DNA-templated | cellular protein metabolic process | regulation of endopeptidase activity | cellular macromolecule biosynthetic process | kinase activity | regulation of cell growth | peptidyl-serine phosphorylation | cellular protein modification process | heterocycle metabolic process | negative regulation of hydrolase activity | positive regulation of metabolic process | positive regulation of Wnt signaling pathway | cellular metabolic process | regulation of cell death | negative regulation of cell death | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | negative regulation of endopeptidase activity | macromolecule metabolic process

GO Cellular Component

PcG protein complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | protein kinase CK2 complex | cell | nuclear lumen | nuclear transcriptional repressor complex | cytoplasm | intracellular organelle | protein-containing complex | histone deacetylase complex | nucleoplasm | plasma membrane | chromatin | nuclear chromosome | Sin3 complex | membrane-bounded organelle | transcriptional repressor complex | nucleus | Sin3-type complex | organelle | SWI/SNF superfamily-type complex | NuRD complex | cell periphery | membrane-enclosed lumen | nuclear chromatin | ATPase complex | cytosol | intracellular | membrane