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QuickView for pyrin (gene)


Gene Symbol:
Mefv Mus musculus Mus musculus
Full name:
Mediterranean fever
Synonyms:
FMF, TRIM20, pyrin, pyrin, familial mediterranean fever, marenostrin
Genomic Location:
Chr 16: 3707215-3718097
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

actin binding | cation binding | cytoskeletal protein binding | identical protein binding | ion binding | protein binding | zinc ion binding | transition metal ion binding | metal ion binding

GO Biological Process

regulation of interleukin-1 beta production | regulation of cysteine-type endopeptidase activity | negative regulation of cytokine production involved in inflammatory response | response to cytokine | regulation of autophagy | negative regulation of cellular process | defense response | negative regulation of inflammatory response | regulation of proteolysis | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | regulation of cellular process | negative regulation of interleukin-1 production | regulation of metabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | response to stimulus | positive regulation of protein metabolic process | positive regulation of peptidase activity | response to stress | positive regulation of cysteine-type endopeptidase activity | positive regulation of proteolysis | regulation of NLRP3 inflammasome complex assembly | regulation of peptidase activity | regulation of catalytic activity | negative regulation of chemokine production | negative regulation of cytokine production | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of hydrolase activity | negative regulation of macrophage inflammatory protein 1 alpha production | negative regulation of interleukin-12 production | regulation of cytokine production involved in inflammatory response | regulation of cellular protein metabolic process | positive regulation of endopeptidase activity | regulation of interleukin-1 production | regulation of cellular metabolic process | inflammatory response | regulation of protein metabolic process | positive regulation of molecular function | response to organic substance | immune response | negative regulation of protein complex assembly | positive regulation of autophagy | response to interferon-gamma | regulation of cytokine production | regulation of endopeptidase activity | negative regulation of interleukin-1 beta production | regulation of chemokine production | negative regulation of NLRP3 inflammasome complex assembly | innate immune response | positive regulation of metabolic process | immune system process | regulation of inflammatory response | regulation of cellular component organization

GO Cellular Component

supramolecular fiber | intracellular membrane-bounded organelle | microtubule associated complex | cytoplasmic vesicle | cell | microtubule | cytoplasm | intracellular organelle | protein-containing complex | cell projection | vesicle | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | intracellular vesicle | cytoskeleton | intracellular | supramolecular complex