Name: | rho-Associated Kinases |
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Description: | A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES. |
Synonyms: |
rho Associated Kinase; rho Associated Coiled Coil Kinase; rho-Kinase; Coiled-Coil Kinase, rho-Associated; rho-Associated Kinase; Protein Kinases, ROCK; ROCK Protein Kinases; rho Associated Kinases; rho Kinase; rho-Associated Coiled-Coil Kinase.
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