QuickView for ribophorin I (gene)

Gene Symbol:

RPN1 Homo sapiens

Full name:

ribophorin I

Synonyms:

OST1, RBPH1, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, RPN-I, dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit, oligosaccharyltransferase 1 homolog, oligosaccharyltransferase complex subunit (non-catalytic), ribophorin-1

Genomic Location:

Chr 3: 129821503-129852409

Description:

This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory...

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This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GCCATNTTG_YY1_Q6 ,  ACTGTGA_MIR27A_MIR27B ,  YY1_Q6

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-27

Cytogenetic Map:

3q21.3

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