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QuickView for sfpq (gene)


Gene Symbol:
SFPQ Homo sapiens Homo sapiens
Full name:
splicing factor proline and glutamine rich
Synonyms:
POMP100, PPP1R140, PSF, splicing factor, proline- and glutamine-rich, 100 kDa DNA-pairing protein, DNA-binding p52/p100 complex, 100 kDa subunit, PTB-associated splicing factor, polypyrimidine tract binding protein associated, polypyrimidine tract-binding protein-associated splicing factor, protein phosphatase 1, regulatory subunit 140, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated), splicing factor proline/glutamine-rich
Genomic Location:
Chr 1: 35421788-35431322
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 1
1p34.3





GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | chromatin binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | E-box binding | DNA binding | sequence-specific double-stranded DNA binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | histone deacetylase binding | heterocyclic compound binding | RNA binding

GO Biological Process

positive regulation of immune response | RNA metabolic process | double-strand break repair | regulation of cell cycle process | positive regulation of macromolecule biosynthetic process | RNA processing | regulation of cellular response to oxidative stress | positive regulation of cellular component organization | regulation of response to oxidative stress | positive regulation of apoptotic process | regulation of programmed cell death | regulation of immune system process | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | histone modification | positive regulation of intrinsic apoptotic signaling pathway | defense response | histone deacetylation | regulation of organelle organization | regulation of chromosome segregation | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | negative regulation of nucleic acid-templated transcription | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of immune response | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | RNA splicing | positive regulation of innate immune response | positive regulation of immune system process | response to stress | RNA splicing, via transesterification reactions | negative regulation of circadian rhythm | cellular nitrogen compound biosynthetic process | activation of innate immune response | rhythmic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | protein modification process | mRNA metabolic process | positive regulation of response to oxidative stress | cellular biosynthetic process | DNA recombination | macromolecule modification | histone H3 deacetylation | alternative mRNA splicing, via spliceosome | DNA repair | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of organelle organization | double-strand break repair via homologous recombination | regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | cellular response to DNA damage stimulus | regulation of intrinsic apoptotic signaling pathway | positive regulation of chromosome organization | positive regulation of cell cycle | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | positive regulation of cellular response to oxidative stress | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | biosynthetic process | protein deacetylation | aromatic compound biosynthetic process | regulation of apoptotic signaling pathway | regulation of cellular metabolic process | positive regulation of sister chromatid cohesion | positive regulation of signal transduction | positive regulation of oxidative stress-induced cell death | regulation of RNA metabolic process | regulation of sister chromatid cohesion | activation of immune response | protein metabolic process | DNA-binding transcription factor activity | regulation of innate immune response | DNA metabolic process | regulation of intracellular signal transduction | regulation of sister chromatid segregation | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | positive regulation of cell death | immune response | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | positive regulation of chromosome segregation | positive regulation of programmed cell death | regulation of chromosome organization | transcription, DNA-templated | positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway | regulation of cell communication | covalent chromatin modification | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | regulation of circadian rhythm | recombinational repair | organelle organization | positive regulation of cell cycle process | cellular protein modification process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | innate immune response | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | immune system process | cellular metabolic process | mRNA processing | regulation of cell death | mRNA splicing, via spliceosome | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process

GO Cellular Component

nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | cytoplasm | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | chromatin | nuclear speck | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear matrix | paraspeckles | intracellular | nuclear periphery