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PubChem
| Name: | Sodium Bicarbonate |
|---|---|
| PubChem Compound ID: | 516892 |
| Description: | A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions. |
| Molecular formula: | CHNaO3 |
| Molecular weight: | 84.0066 g/mol |
| Synonyms: |
Sodium bicarbonate
|
DrugBank
Identification
| Name: | Sodium Bicarbonate |
|---|---|
| Name (isomeric): | DB01390 |
| Drug Type: | small molecule |
| Description: | A white, crystalline powder that is commonly used as a pH buffering agent, an electrolyte replenisher, systemic alkalizer and in topical cleansing solutions. |
| Synonyms: |
Sodium hydrogen carbonate; Sodium hydrocarbonate; Bicarbonate of soda; Sodium hydrogencarbonate; Sodium acid carbonate; Carbonic acid monosodium salt
|
| Brand: | Colovage, Sodium bicarbonate in plastic container, Meylon, OCL, Acidosan, Glycoprep, BSS plus, Neut, Colyte, Gripe water, Peg-lyte, Co-lav, Natrum bicarbonicum, E-Z-EM Prep Lyte, Citrocarbonate, Hema BP-38, Go-evac, Sandoz sodium bicarbonate, Sodium bicarbonate liquid concentrate, Golytely, Baros, Nulytely, Endosol extra, 800 Sodium Bicarbonate Powder, Elliotts B solution |
| Brand name mixture: | Woodward's Gripe Water(Oil of Dill + Sodium Bicarbonate), E-Z-Gas 2(Citric Acid + Sodium Bicarbonate), Alka-Seltzer Flavoured(Acetylsalicylic Acid + Citric Acid + Sodium Bicarbonate), Artrol(Antipyrine + Cimicifuga Racemosa + Methyl Salicylate + Sodium Bicarbonate + Sodium Salicylate + Taraxacum Officinale Weber), Baros Effervescent Granules(Sod... show more » |
| Category: | Antidiarrheals |
| CAS number: | 144-55-8 |
Pharmacology
| Indication: | Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis. Also is indicated in severe diarrhea which is often accompanied by a significant loss of bicarbonate. Further indicated in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturateprotein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of blood pigments. |
|---|---|
| Pharmacology: | Intravenous sodium bicarbonate therapy increases plasma bicarbonate, buffers excess hydrogen ion concentration, raises blood pH and reverses the clinical manifestations of acidosis. |
| Mechanism of Action: |
Sodium bicarbonate is a systemic alkalizer, which increases plasma bicarbonate, buffers excess hydrogen ion concentration, and raises blood pH, thereby reversing the clinical manifestations of acidosis. It is also a urinary alkalizer, increasing the excretion of free bicarbonate ions in the urine, thus effectively raising the urinary pH. By maintai...
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| Affected organisms: | Humans and other mammals |
Interactions
| Drug interaction: |
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Targets
Transporters
