QuickView for son (gene)

Gene Symbol:

SON Homo sapiens

Full name:

SON DNA binding protein

Synonyms:

BASS1, C21orf50, DBP-5, NREBP, SON3, TOKIMS, protein SON, Bax antagonist selected in Saccharomyces 1, NRE-binding protein, negative regulatory element-binding protein

Genomic Location:

Chr 21: 33837220-33871682

Description:

This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this g...

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This gene encodes a protein that contains multiple simple repeats. The encoded protein binds RNA and promotes pre-mRNA splicing, particularly of transcripts with poor splice sites. The protein also recognizes a specific DNA sequence found in the human hepatitis B virus (HBV) and represses HBV core promoter activity. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  HNF4ALPHA_Q6 ,  GTGTTGA_MIR505 ,  MAZR_01 ,  AAGCCAT_MIR135A_MIR135B ,  GCATTTG_MIR105 ,  AACTGAC_MIR223 ,  AGCGCTT_MIR518F_MIR518E_MIR518A ,  TTTGTAG_MIR520D ,  CAGTGTT_MIR141_MIR200A ,  AREB6_04 ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  ACTTTAT_MIR1425P ,  AGGAGTG_MIR483 ,  AAGCAAT_MIR137 ,  CTTTGTA_MIR524 ,  GGGAGGRR_MAZ_Q6 ,  CDPCR3HD_01 ,  TCTGATA_MIR361 ,  TCCCRNNRTGC_UNKNOWN ,  GCACCTT_MIR18A_MIR18B ,  NFY_Q6_01 ,  ALPHACP1_01 ,  ATF_01 ,  CAGCTTT_MIR320 ,  ACCAAAG_MIR9 ,  CDPCR1_01 ,  ATGTTAA_MIR302C ,  TGCTGAY_UNKNOWN ,  ATGTTTC_MIR494 ,  CTCTGGA_MIR520A_MIR525 ,  NFY_Q6 ,  CTTTAAR_UNKNOWN ,  ATACTGT_MIR144 ,  GGCACTT_MIR519E ,  SCGGAAGY_ELK1_02 ,  GGCCAGT_MIR193A_MIR193B ,  TCCATTKW_UNKNOWN ,  RCGCANGCGY_NRF1_Q6 ,  TAANNYSGCG_UNKNOWN ,  ELK1_02 ,  MZF1_02 ,  ACAGGGT_MIR10A_MIR10B ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  DR4_Q2 ,  RRCCGTTA_UNKNOWN ,  HOX13_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-10 ,  Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-142-5p ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-18 ,  Predicted Gene Targets for miR-193 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-223 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-338 ,  Predicted Gene Targets for miR-361 ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-505 ,  Predicted Gene Targets for miR-543

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Cytogenetic Map:

21q22.11

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