Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for spermine (compound)


PubChem
Name: Spermine
PubChem Compound ID: 10488434
Description: A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Molecular formula: C10H26N4
Molecular weight: 204.326 g/mol
DrugBank
Identification
Name: Spermine
Name (isomeric): DB00127
Drug Type: small molecule
Description: A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Synonyms:
1, 4-Bis(aminopropyl)butanediamine; Spermin; Spermine dihydrate; 4,9-Diaza-1,12-dodecanediamine; 4,9-Diazadodecane-1,12-diamine
Brand: Musculamine, Neuridine, Gerontine
Category: Micronutrient, Dietary supplement
CAS number: 71-44-3
Pharmacology
Indication: For nutritional supplementation, also for treating dietary shortage or imbalance
Pharmacology: Spermine is a polyamine. It is an organic molecule that is involved in cellular metabolism.
Mechanism of Action:
Spermine is derived from spermidine by spermine synthase. Spermine is a polyamine, a small organic cations that is absolutely required for eukaryotic cell growth. Spermine, is normally found in millimolar concentrations in the nucleus. Spermine functions directly as a free radical scavenger, and forms a variety of adducts that prevent oxidative dam...
show more »
Affected organisms: Humans and other mammals

Targets


Enzymes


Transporters