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QuickView for stathmin 1 (gene)


Gene Symbol:
STMN1 Homo sapiens Homo sapiens
Full name:
stathmin 1
Synonyms:
C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN, stathmin, leukemia-associated phosphoprotein p18, metablastin, oncoprotein 18, phosphoprotein 19, phosphoprotein p19, prosolin, stathmin 1/oncoprotein 18, testicular tissue protein Li 189, transmembrane protein C1orf215
Genomic Location:
Chr 1: 26099194-26105955
Description:
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and pr...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
TGGAAA_NFAT_Q4_01 GATTGGY_NFY_Q6_01 MYOD_Q6_01 SP1_01 CMYB_01 SMTTTTGT_UNKNOWN MCAATNNNNNGCG_UNKNOWN USF_Q6 ARNT_01 MYC_Q2
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 1
1p36.11





GO Molecular Function

cytoskeletal protein binding | protein binding | tubulin binding

GO Biological Process

mitotic cytokinesis | negative regulation of G-protein coupled receptor protein signaling pathway | negative regulation of thrombin-activated receptor signaling pathway | brain development | regulation of supramolecular fiber organization | cell morphogenesis | response to virus | microtubule cytoskeleton organization involved in mitosis | regulation of microtubule polymerization or depolymerization | neuron projection morphogenesis | negative regulation of stress fiber assembly | intracellular signal transduction | regulation of localization | negative regulation of cellular process | microtubule cytoskeleton organization | cell differentiation | negative regulation of actin filament bundle assembly | nervous system development | cell part morphogenesis | neurogenesis | regulation of organelle organization | positive regulation of cellular component movement | generation of neurons | microtubule-based process | cellular process | cell projection morphogenesis | negative regulation of signaling | neuron development | cytoskeleton-dependent cytokinesis | negative regulation of microtubule polymerization or depolymerization | regulation of binding | regulation of cellular process | regulation of protein complex assembly | cellular component organization | head development | response to stimulus | cell morphogenesis involved in neuron differentiation | mitotic spindle organization | multicellular organismal homeostasis | supramolecular fiber organization | water homeostasis | response to external biotic stimulus | system development | regulation of signal transduction | regulation of actin cytoskeleton organization | multicellular organism development | negative regulation of guanyl-nucleotide exchange factor activity | regulation of actin filament organization | regulation of actomyosin structure organization | regulation of small GTPase mediated signal transduction | axon development | hepatocyte growth factor receptor signaling pathway | cell cycle | enzyme linked receptor protein signaling pathway | regulation of cellular component movement | axonogenesis | negative regulation of binding | regulation of Rho protein signal transduction | cell division | cytokinesis | microtubule depolymerization | skin development | cell morphogenesis involved in differentiation | negative regulation of microtubule polymerization | cell communication | negative regulation of protein binding | homeostatic process | cellular protein complex disassembly | regulation of microtubule-based process | positive regulation of molecular function | neuron differentiation | negative regulation of protein polymerization | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | cell projection organization | regulation of microtubule polymerization | regulation of body fluid levels | negative regulation of cytoskeleton organization | chemical homeostasis | regulation of GTP binding | negative regulation of Rho protein signal transduction | neuron projection development | negative regulation of protein complex assembly | regulation of water loss via skin | animal organ development | negative regulation of small GTPase mediated signal transduction | negative regulation of Ras protein signal transduction | cytoskeleton organization | protein depolymerization | positive regulation of binding | microtubule polymerization or depolymerization | regulation of stress fiber assembly | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of protein binding | cell development | protein-containing complex disassembly | regulation of Ras protein signal transduction | anatomical structure morphogenesis | regulation of actin filament bundle assembly | response to biotic stimulus | establishment of skin barrier | regulation of G-protein coupled receptor protein signaling pathway | developmental process | organelle organization | multicellular organismal water homeostasis | negative regulation of supramolecular fiber organization | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | regulation of actin filament-based process | spindle organization | regulation of microtubule cytoskeleton organization | regulation of cellular component organization | regulation of cytoskeleton organization | response to other organism | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

supramolecular fiber | neuron projection | cell | microtubule | cytoplasm | intracellular organelle | cell projection | vesicle | extracellular exosome | microtubule cytoskeleton | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | cytoskeleton | intracellular | membrane | supramolecular complex