QuickView for synC (gene)

Gene Symbol:

SYNC Homo sapiens

Full name:

syncoilin, intermediate filament protein

Synonyms:

SYNC1, SYNCOILIN, syncoilin, intermediate filament protein syncoilin, syncoilin intermediate filament 1, syncoilin-1

Genomic Location:

Chr 1: 32918548-32933460

Description:

This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a...

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This gene encodes a member of the intermediate filament family which contains an N-terminal head domain, followed by a central coiled-coil region and a short C-terminal tail. The protein is highly expressed in skeletal and cardiac muscle. The protein links the dystrophin associated protein complex (DAPC) to desmin filaments in muscle and may have a structural role in striated muscle. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  ACAACTT_MIR382 ,  DR3_Q4 ,  AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D ,  PEA3_Q6 ,  AAGCAAT_MIR137 ,  HEB_Q6 ,  GGGAGGRR_MAZ_Q6 ,  AP4_01 ,  TGCCTTA_MIR124A ,  NERF_Q2 ,  AAGCACT_MIR520F ,  AAAGGAT_MIR501 ,  CAGCTG_AP4_Q5 ,  MYB_Q3

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-136 ,  Predicted Gene Targets for miR-382 ,  Predicted Gene Targets for miR-93 ,  Predicted Gene Targets for miR-124a ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-137

Cytogenetic Map:

1p35.1

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