QuickView for taip-3 (gene)

Gene Symbol:

CSRNP1 Homo sapiens

Full name:

cysteine and serine rich nuclear protein 1

Synonyms:

AXUD1, CSRNP-1, FAM130B, TAIP-3, URAX1, cysteine/serine-rich nuclear protein 1, AXIN1 up-regulated 1, TGF-beta-induced apoptosis protein 3, axin-1 up-regulated gene 1 protein

Genomic Location:

Chr 3: 39158350-39170105

Description:

This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased le...

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This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MYOD_Q6_01 ,  HNF4ALPHA_Q6 ,  TGANTCA_AP1_C ,  OCT1_B ,  RYTTCCTG_ETS2_B ,  TGGNNNNNNKCCAR_UNKNOWN ,  E2F1_Q4_01 ,  OCT_Q6 ,  NGFIC_01 ,  YATTNATC_UNKNOWN ,  E2F_Q6_01 ,  OCT1_Q5_01 ,  EGR2_01 ,  TGACCTY_ERR1_Q2 ,  E2F1_Q4 ,  ACTGTGA_MIR27A_MIR27B ,  GGGAGGRR_MAZ_Q6 ,  GGGYGTGNY_UNKNOWN ,  CAGGTG_E12_Q6 ,  BACH2_01 ,  NF1_Q6 ,  GTGCCAA_MIR96 ,  TGCCAAR_NF1_Q6 ,  HSF_Q6 ,  NF1_Q6_01 ,  E2F_03 ,  E2F_Q4_01 ,  BACH1_01 ,  USF_Q6_01 ,  AACTTT_UNKNOWN ,  TGACATY_UNKNOWN ,  ETS1_B ,  E2F_Q3_01 ,  EGR3_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-96 ,  Predicted Gene Targets for miR-31

Cytogenetic Map:

3p22.2

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