QuickView for tpis (gene)
- Gene Symbol:
- SPAG1
Homo sapiens - Full name:
- sperm associated antigen 1
- Synonyms:
- CILD28, CT140, HEL-S-268, HSD-3.8, SP75, TPIS, sperm-associated antigen 1, TPR-containing protein involved in spermatogenesis, epididymis secretory protein Li 268, infertility-related sperm protein Spag-1, tetratricopeptide repeat-containing protein
- Genomic Location:
- Chr 8: 101239439-101323306
- Description:
-
The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm ant...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Bos taurus , Danio rerio , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
8q22.2
GO Molecular Function
guanyl ribonucleotide binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | catalytic activity | anion binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | GTP binding | nucleoside binding | purine ribonucleotide binding | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding
GO Biological Process
axoneme assembly | microtubule bundle formation | microtubule cytoskeleton organization | microtubule-based process | cellular process | cellular component organization | axonemal dynein complex assembly | reproduction | cellular component assembly | organelle assembly | reproductive process | cell projection assembly | fertilization | cellular protein-containing complex assembly | single fertilization | protein-containing complex assembly | cell projection organization | cilium assembly | cytoskeleton organization | cilium organization | organelle organization | sexual reproduction
GO Cellular Component
cell | cytoplasm | cytosol | intracellular
