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QuickView for vasopressin (compound)

Name: Vasopressin (USP)
Name (isomeric): DB00067
Drug Type: biotech
Description: A pharmaceutical preparation containing a mixture of arg-vasopressin and lys-vasopressin. It is prepared by synthesis or obtained from neurohypophyseal extract of domestic animals. Its vasopressor activity is not less than 300 USP vasopressin units per mg.
Arginine oxytocin; Vasopressin, isoleucyl; Pitressin tannate; 3-Isoleucyl vasopressin; Argiprestocin; Vasotocin; Arginine vasotocin; Vasopressin, non-mammalian
Brand: Pressyn, Pitressin
Category: Oxytocics, Antidiuretics, Vasoconstrictor Agents
CAS number: 11000-17-2
Indication: For the treatment of enuresis, polyuria, diabetes insipidus, polydipsia and oesophageal varices with bleeding
Vasopressin is an antidiuretic hormone indicated for the prevention and treatment of postoperative abdominal distention, in abdominal roentgenography to dispel interfering gas shadows, and in diabetes insipidus. Vasopressin can cause contraction of smooth muscle of the gastrointestinal tract and of all parts of the vascular bed, especially the capi...
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Mechanism of Action:
Vasopressin acts on three different receptors, vasopressin receptor V1a (which initiates vasoconstriction, liver gluconeogenesis, platelet aggregation and release of factor VIII), vasopressin receptor V1b (which mediates corticotrophin secretion from the pituitary) and vasopressin receptor V2 which controls free water reabsorption in the renal medu...
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Protein binding: 1%
Biotransformation: The majority of a dose of vasopressin is metabolized and rapidly destroyed in the liver and kidneys.
Half Life: 10-20 minutes
Affected organisms: Humans and other mammals