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QuickView for vitamin C (compound)


PubChem
Name: Ascorbic Acid
PubChem Compound ID: 114765
Description: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Molecular formula: C6H7O6-
Molecular weight: 175.116 g/mol
Synonyms:
L-ascorbate(1-); 299-36-5; CHEBI:13861; Vitamin C; L-Ascorbic acid, ion(1-); Ascorbate; (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; Ascorbate anion; L-Ascorbate
DrugBank
Identification
Name: Ascorbic Acid
Name (isomeric): DB00126
Drug Type: small molecule
Description: A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables. Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. Its biologically active form, vitamin C, functions as a reducing agent and coenzyme in several metabolic pathways. Vitamin C is considered an antioxidant.
Synonyms:
AA; Ascorbic Acid; L-Ascorbic Acid; L-Xyloascorbic Acid; L-Lyxoascorbic Acid; Ascorbate; L-Ascorbate
Brand: Cegiolan, Catavin C, Ascorbutina, Cewin, Colascor, Concemin, Redoxon, Cantan, Cenolate, Duoscorb, Ascorteal, Hybrin, Cevitamin, C-Span, C-Vimin, Testascorbic, Lemascorb, Meri-C, Cevalin, Cetane-Caps Td, Cee-Caps Td, Cereon, Vitacimin, Planavit C, Scorbu-C, Ascorin, Cetane-Caps Tc, Sodascorbate, Cevi-Bid, Cipca, Citriscorb, Ascoltin, Cemagyl, Ascorbin, C-Long, Natrascorb, Cevex, Kyselina Askorbova, Vitace, Cetebe, Secorbate, Cee-Vite, Viscorin, Cenetone, Celaskon, Cergona, Laroscorbine, Cantaxin, Ce Lent, Cevitan, Liqui-Cee, Vitascorbol, Cevimin, Vitacin, Cevital, Ascorb, Arco-Cee, Xitix, Ascorvit, Cemill, Vicomin C, Ribena, Ascorbicab, Cescorbat, Cebid, Ascorbicin, Cebicure, C-Level, Ascorbicap, Cevatine, Cecon, Ascor-B.I.D., Cebion, Vicin, Cetane, Antiscorbutic Vitamin, Cetemican, Scorbacid, Ceglion, IDO-C, Adenex, Cetamid, Allercorb, Hicee, Ascorbajen, Proscorbin, Ciamin, Celin, Antiscorbic Vitamin, Vitamisin, Viforcit, Cevitex, Cevitamic Acid, Cebione, C-Quin, Davitamon C, Vitacee, Roscorbic, Vicelat
Category: Vitamins (Vitamin C), Essential Vitamins, Antioxidants, Vitamins, Free Radical Scavengers
CAS number: 50-81-7
Pharmacology
Indication: Used to treat vitamin C deficiency, scurvy, delayed wound and bone healing, urine acidification, and in general as an antioxidant. It has also been suggested to be an effective antiviral agent.
Pharmacology: Ascorbic Acid (vitamin C) is a water-soluble vitamin indicated for the prevention and treatment of scurvy, as ascorbic acid deficiency results in scurvy. Collagenous structures are primarily affected, and lesions develop in bones and blood vessels. Administration of ascorbic acid completely reverses the symptoms of ascorbic acid deficiency.
Mechanism of Action:
In humans, an exogenous source of ascorbic acid is required for collagen formation and tissue repair by acting as a cofactor in the posttranslational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. These two forms of the vitamin are b...
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Absorption: 70% to 90%
Protein binding: 25%
Biotransformation: Hepatic. Ascorbic acid is reversibly oxidised (by removal of the hydrogen from the enediol group of ascorbic acid) to dehydroascorbic acid. The two forms found in body fluids are physiologically active. Some ascorbic acid is metabolized to inactive compounds including ascorbic acid-2-sulfate and oxalic acid.
Half Life: 16 days (3.4 hours in people who have excess levels of vitamin C)
Affected organisms: Humans and other mammals
Interactions
Drug interaction:
IndinavirVitamin C decreases indinavir levels
DeferoxamineVitamin C may increase the adverse effects of deferoxamine. Transient deterioration of left ventricular function has been observed during concomitant therapy. Use caution during concomitant therapy.

Targets