QuickView for vsx2 (gene)
- Gene Symbol:
- VSX2
Homo sapiens - Full name:
- visual system homeobox 2
- Synonyms:
- CHX10, HOX10, MCOP2, MCOPCB3, RET1, visual system homeobox 2, ceh-10 homeo domain containing homolog, ceh-10 homeodomain-containing homolog, homeobox protein CHX10
- Genomic Location:
- Chr 14: 73775928-73799194
- Description:
-
This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
14q24.3
GO Molecular Function
sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | DNA binding | organic cyclic compound binding | DNA-binding transcription factor activity | heterocyclic compound binding
GO Biological Process
RNA metabolic process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cellular process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | response to stimulus | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | multicellular organism development | regulation of gene expression | nervous system process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | anatomical structure development | metabolic process | visual perception | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | organic substance metabolic process | sensory perception of light stimulus | gene expression | transcription, DNA-templated | sensory perception | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
