QuickView for vwf (gene)

Gene Symbol:

VWF Homo sapiens

Full name:

von Willebrand factor

Synonyms:

F8VWF, VWD, von Willebrand factor, coagulation factor VIII VWF

Genomic Location:

Chr 12: 5928301-6104097

Description:

This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand dise...

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This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Canis lupus familiaris ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CATTGTYY_SOX9_B1 ,  RREB1_01 ,  CAGGTG_E12_Q6 ,  AREB6_01 ,  GCM_Q2 ,  HAND1E47_01 ,  TAATTA_CHX10_01 ,  TTGTTT_FOXO4_01 ,  PAX_Q6

Cytogenetic Map:

12p13.31

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