QuickView for AANAT;jsessionid=6B51CBC0AE6CA4E4DC5F0C192344E47F;jsessionid=28A8D48ECDB2F98A3D59DAFD67D773A2;jsessionid=5DD31286107539E34969DC103DE5919B (gene)
- Gene Symbol:
- Aanat
Mus musculus - Full name:
- arylalkylamine N-acetyltransferase
- Synonyms:
- AA-NAT, Nat-2, Nat4, Snat, serotonin N-acetyltransferase, aralkylamine N-acetyltransferase, serotonin acetylase
- Genomic Location:
- Chr 11: 116455001-116458858
- Description:
-
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cA...
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
N-acetyltransferase activity | arylamine N-acetyltransferase activity | transferase activity, transferring acyl groups other than amino-acyl groups | 14-3-3 protein binding | N-acyltransferase activity | catalytic activity | transferase activity, transferring acyl groups | protein binding | aralkylamine N-acetyltransferase activity | transferase activity | acetyltransferase activity
GO Biological Process
response to radiation | response to hormone | response to metal ion | N-terminal protein amino acid modification | response to organophosphorus | cellular process | N-terminal protein amino acid acetylation | response to inorganic substance | response to peptide hormone | response to prostaglandin | organic cyclic compound metabolic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | response to stimulus | cellular nitrogen compound biosynthetic process | response to peptide | circadian rhythm | response to alcohol | rhythmic process | cellular nitrogen compound metabolic process | cellular response to organic cyclic compound | protein modification process | cellular biosynthetic process | macromolecule modification | response to nitrogen compound | response to light stimulus | nitrogen compound metabolic process | protein acetylation | hormone biosynthetic process | response to purine-containing compound | response to fatty acid | regulation of hormone levels | melatonin biosynthetic process | response to prostaglandin E | response to ketone | response to lipid | cellular amide metabolic process | biosynthetic process | aromatic compound biosynthetic process | protein maturation | response to zinc ion | drug metabolic process | protein metabolic process | response to organic substance | response to insulin | metabolic process | melatonin metabolic process | organic substance metabolic process | response to copper ion | gene expression | amide biosynthetic process | cellular response to cAMP | response to cAMP | response to organic cyclic compound | cellular protein metabolic process | hormone metabolic process | cellular protein modification process | indole-containing compound biosynthetic process | response to organonitrogen compound | photoperiodism | heterocycle metabolic process | cellular metabolic process | cellular response to organic substance | macromolecule metabolic process
GO Cellular Component
cell | cytoplasm | perinuclear region of cytoplasm | cytosol | intracellular
