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QuickView for ABCC1;jsessionid=20120A56C17D7A0C2063B7E0C56A2D41;jsessionid=A191EEE7ECE47758AEA073E3955D5F9C (gene)


Gene Symbol:
Abcc1 Rattus norvegicus Rattus norvegicus
Full name:
ATP binding cassette subfamily C member 1
Synonyms:
Abcc1a, Avcc1a, Mrp, Mrp1, multidrug resistance-associated protein 1, ATP-binding cassette sub-family C ( CFTR/MRP) member 1a, ATP-binding cassette sub-family C member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C, member 1-like, ATP-binding cassette, subfamily C (CFTR/MRP), member 1, LTC4 transporter, leukotriene C(4) transporter, multidrug resistance protein 1, multidrug resistance-associated protein 1-like, multiple drug resistance-associated protein
Genomic Location:
Chr 10: 452239-575705
Description:
ATP-binding cassette (ABC) multiple drug resistance protein involved in the release of glutathione synthase during oxidative stress
Orthologs:
Homo sapiens Mus musculus D. melanogaster C. elegans Saccharomyces cerevisiae Danio rerio Schizosaccharomyces pombe Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_022281
XM_001053148
Protein Names
Q810E4
Q8CG09
Q810G9
Q9JHS0
Q63346



GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | anion transmembrane transporter activity | xenobiotic transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | sphingolipid transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | oligopeptide transmembrane transporter activity | ATP binding | tripeptide transmembrane transporter activity | phospholipid transporter activity | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | drug transmembrane transporter activity | glutathione S-conjugate-exporting ATPase activity | purine ribonucleoside triphosphate binding | peptide transmembrane transporter activity | long-chain fatty acid transporter activity | hydrolase activity, acting on acid anhydrides | lipid-transporting ATPase activity | glutathione transmembrane transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | efflux transmembrane transporter activity | drug binding | sphingolipid-translocating ATPase activity | xenobiotic transmembrane transporting ATPase activity | lipid transporter activity | heterocyclic compound binding | oxidoreductase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding | phospholipid-translocating ATPase activity

GO Biological Process

long-chain fatty acid transport | positive regulation of locomotion | plasma membrane long-chain fatty acid transport | cell motility | regulation of localization | lipid transport | ATPase activity, coupled to transmembrane movement of substances | organic anion transmembrane transporter activity | establishment of localization | oligopeptide transport | negative regulation of neuron death | anion transmembrane transporter activity | negative regulation of cellular process | response to drug | xenobiotic transmembrane transporter activity | positive regulation of cellular component movement | glutathione transmembrane transport | membrane organization | regulation of neuron death | cellular process | monocarboxylic acid transport | regulation of cell motility | localization | anion transport | macromolecule localization | regulation of membrane lipid distribution | regulation of cellular process | transmembrane transporter activity | sphingolipid transporter activity | cellular component organization | drug export | response to stimulus | response to stress | regulation of response to drug | sphingolipid translocation | oligopeptide transmembrane transport | carboxylic acid transmembrane transport | cell chemotaxis | oligopeptide transmembrane transporter activity | locomotion | tripeptide transmembrane transporter activity | cell migration | phospholipid transporter activity | ion transmembrane transport | fatty acid transport | organic substance transport | regulation of cell migration | active transmembrane transporter activity | peptide transport | regulation of cellular component movement | response to oxidative stress | organic acid transport | ion transmembrane transporter activity | positive regulation of cell migration | glutathione transport | organic anion transport | positive regulation of drug transmembrane export | tripeptide transport | positive regulation of response to drug | drug transmembrane transporter activity | glutathione S-conjugate-exporting ATPase activity | regulation of locomotion | positive regulation of transport | peptide transmembrane transporter activity | phospholipid transport | xenobiotic transport | anion transmembrane transport | phospholipid efflux | organic acid transmembrane transport | cofactor transport | metabolic process | lipid localization | long-chain fatty acid transporter activity | oxidation-reduction process | amide transport | drug transport | fatty acid transmembrane transport | lipid-transporting ATPase activity | transmembrane transport | glutathione transmembrane transporter activity | drug transmembrane transport | carboxylic acid transport | efflux transmembrane transporter activity | sphingolipid-translocating ATPase activity | phospholipid translocation | xenobiotic transmembrane transporting ATPase activity | regulation of transport | lipid transporter activity | ion transport | regulation of cell death | positive regulation of cell motility | oxidoreductase activity | negative regulation of cell death | chemotaxis | phospholipid-translocating ATPase activity

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | plasma membrane | vacuole | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | basolateral plasma membrane | intracellular | membrane | intrinsic component of plasma membrane | vacuolar membrane