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QuickView for ABCG2;jsessionid=0B427F43DADB18D02A91AE5580EB81E7;jsessionid=3F1F8CC2AAA099488E86AD529704D684;jsessionid=300C2238BDAF55FDE9CF11E4343A3361;jsessionid=8D58EAFDD95FFDF54E33BFD74CF7310A (gene)


Gene Symbol:
Abcg2 Mus musculus Mus musculus
Full name:
ATP binding cassette subfamily G member 2 (Junior blood group)
Synonyms:
ABC15, ABCP, AI428558, BCRP, Bcrp1, MXR, MXR1, ATP-binding cassette sub-family G member 2, ATP-binding cassette, sub-family G (WHITE), member 2, breast cancer resistance protein 1 homolog, mitoxantrone resistance protein 1, urate exporter
Genomic Location:
Chr 6: 58546666-58642445
Description:
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the Whit...
Orthologs:
Homo sapiens Rattus norvegicus Saccharomyces cerevisiae Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | xenobiotic transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | cholesterol transporter activity | catalytic activity | ATP binding | cytoskeletal protein binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | identical protein binding | sterol transporter activity | ion binding | organic cyclic compound binding | drug transmembrane transporter activity | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | xenobiotic transmembrane transporting ATPase activity | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

regulation of localization | lipid transport | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | response to drug | xenobiotic transmembrane transporter activity | glucuronoside metabolic process | cellular process | localization | female pregnancy | anion transport | regulation of digestive system process | multicellular organismal reproductive process | macromolecule localization | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | drug export | response to stimulus | reproduction | organic hydroxy compound transport | cellular nitrogen compound metabolic process | cholesterol transporter activity | negative regulation of transport | embryo development | urate metabolic process | nitrogen compound metabolic process | reproductive process | multicellular organism development | regulation of intestinal absorption | organic substance transport | active transmembrane transporter activity | small molecule metabolic process | cellular carbohydrate metabolic process | sterol transporter activity | sterol transport | organic anion transport | carbohydrate metabolic process | cholesterol transport | cholesterol efflux | drug transmembrane transporter activity | negative regulation of intestinal absorption | embryo development ending in birth or egg hatching | carboxylic acid metabolic process | multicellular organism reproduction | xenobiotic transport | anatomical structure development | metabolic process | lipid localization | glycoside metabolic process | organic substance metabolic process | drug transport | transmembrane transport | organic acid metabolic process | drug transmembrane transport | urate transport | developmental process | xenobiotic transmembrane transporting ATPase activity | carbohydrate derivative metabolic process | regulation of transport | heterocycle metabolic process | embryonic process involved in female pregnancy | lipid transporter activity | ion transport | cellular metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | apical plasma membrane | cell | cytoplasm | intracellular organelle | receptor complex | apical part of cell | protein-containing complex | plasma membrane | mitochondrion | membrane-bounded organelle | nucleus | organelle | cell periphery | intracellular | membrane