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QuickView for ABCG2;jsessionid=0B427F43DADB18D02A91AE5580EB81E7;jsessionid=8B39CEB9F327AEC3A2B2D114F6FDDFD8;jsessionid=166D80DC537E46EAAA8469B1342FA9B7;jsessionid=0C27ADC84ECB5B170824F3811CF5B896 (gene)


Gene Symbol:
ABCG2 Homo sapiens Homo sapiens
Full name:
ATP binding cassette subfamily G member 2 (Junior blood group)
Synonyms:
ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR-1, MXR1, UAQTL1, ATP-binding cassette sub-family G member 2, ABC transporter, ATP-binding cassette transporter G2, ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group), breast cancer resistance protein, mitoxantrone resistance-associated protein, multi drug resistance efflux transport ATP-binding cassette sub-family G (WHITE) member 2, placenta specific MDR protein, placenta-specific ATP-binding cassette transporter, urate exporter
Genomic Location:
Chr 4: 89230440-89299035
Description:
The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the Whit...
Orthologs:
Mus musculus Rattus norvegicus Saccharomyces cerevisiae Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 4
4q22.1





GO Molecular Function

ATPase activity, coupled to transmembrane movement of substances | xenobiotic transmembrane transporter activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | cholesterol transporter activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | active transmembrane transporter activity | purine nucleotide binding | transporter activity | identical protein binding | sterol transporter activity | ion binding | organic cyclic compound binding | drug transmembrane transporter activity | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | hydrolase activity, acting on acid anhydrides | heme transporter activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | xenobiotic transmembrane transporting ATPase activity | lipid transporter activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

lipid transport | ATPase activity, coupled to transmembrane movement of substances | establishment of localization | response to drug | xenobiotic transmembrane transporter activity | cellular chemical homeostasis | cellular process | localization | cellular homeostasis | macromolecule localization | transmembrane transporter activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | organic hydroxy compound transport | cellular nitrogen compound metabolic process | cholesterol transporter activity | urate metabolic process | metal ion homeostasis | nitrogen compound metabolic process | organic substance transport | cellular ion homeostasis | active transmembrane transporter activity | small molecule metabolic process | sterol transporter activity | sterol transport | cholesterol transport | cholesterol efflux | cation homeostasis | cellular cation homeostasis | drug transmembrane transporter activity | homeostatic process | iron ion homeostasis | xenobiotic transport | cofactor transport | metabolic process | lipid localization | chemical homeostasis | heme transporter activity | organic substance metabolic process | ion homeostasis | cellular iron ion homeostasis | drug transport | transmembrane transport | organic acid metabolic process | drug transmembrane transport | heme transport | xenobiotic transmembrane transporting ATPase activity | cellular metal ion homeostasis | heterocycle metabolic process | lipid transporter activity | transition metal ion homeostasis | cellular metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | apical plasma membrane | organelle membrane | cell | cytoplasm | intracellular organelle | receptor complex | apical part of cell | protein-containing complex | plasma membrane | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | cell periphery | mitochondrial membrane | intracellular | membrane