QuickView for ACHE;jsessionid=7734803E1AC0BBA983F08C5C872AAB6A;jsessionid=718E67E451FC185E28422B990CD88E4A (gene)
- Gene Symbol:
- Ache
Rattus norvegicus - Full name:
- acetylcholinesterase
- Synonyms:
- acetylcholinesterase, glycolipid-anchored form of acetylcholinesterase
- Genomic Location:
- N/A
- Description:
-
catalyzes the hydrolysis of acetylcholine to choline and acetate; plays a role in neuronal development and synapse formation
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Danio rerio , Gallus gallus , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
protein self-association | cation binding | neurotransmitter binding | protein-containing complex binding | carboxylic ester hydrolase activity | hydrolase activity | cholinesterase activity | choline binding | catalytic activity | extracellular matrix binding | serine hydrolase activity | collagen binding | hydrolase activity, acting on ester bonds | identical protein binding | ion binding | acetylcholine binding | hormone binding | laminin binding | protein binding | protein homodimerization activity | protein dimerization activity | drug binding | acetylcholinesterase activity
GO Biological Process
positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cell development | eye development | establishment of localization | neuron death | positive regulation of developmental process | acetylcholine catabolic process | cell differentiation | nervous system development | positive regulation of axonogenesis | neurogenesis | generation of neurons | cellular process | organic substance catabolic process | localization | chemical synaptic transmission | synapse assembly | acetylcholine catabolic process in synaptic cleft | neurotransmitter receptor biosynthetic process | osteoblast development | regulation of neuron projection development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | catabolic process | cellular component organization | choline metabolic process | positive regulation of dendrite morphogenesis | positive regulation of cold-induced thermogenesis | cellular component assembly | cell-cell signaling | drug catabolic process | receptor biosynthetic process | regulation of neurotransmitter levels | system development | nitrogen compound metabolic process | positive regulation of neuron projection development | multicellular organism development | regulation of axonogenesis | protein complex oligomerization | regulation of hormone levels | regulation of neuron differentiation | synaptic signaling | positive regulation of cell projection organization | vesicle-mediated transport | synapse organization | positive regulation of cell differentiation | neurotransmitter metabolic process | biosynthetic process | protein tetramerization | neurotransmitter catabolic process | sensory organ development | cell communication | regulation of cellular metabolic process | receptor internalization | positive regulation of dendrite development | drug metabolic process | protein-containing complex assembly | regulation of cell morphogenesis involved in differentiation | retina development in camera-type eye | hormone catabolic process | import into cell | anatomical structure development | regulation of dendrite morphogenesis | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | endocytosis | cell adhesion | organic substance metabolic process | cell death | animal organ development | acetylcholine metabolic process | camera-type eye development | regulation of dendrite development | signaling | cell development | hormone metabolic process | regulation of nervous system development | regulation of developmental process | receptor-mediated endocytosis | developmental process | neurotransmitter receptor metabolic process | synaptic transmission, cholinergic | regulation of receptor recycling | receptor metabolic process | positive regulation of metabolic process | ossification | positive regulation of neuron differentiation | osteoblast differentiation | regulation of cell projection organization | cellular metabolic process | positive regulation of cell morphogenesis involved in differentiation | regulation of cellular component organization | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
presynaptic membrane | synaptic cleft | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | axolemma | somatodendritic compartment | cell projection membrane | neuromuscular junction | cell body | cell | neuronal cell body | distal axon | intrinsic component of membrane | synaptic membrane | terminal bouton | external side of plasma membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | leading edge membrane | main axon | presynapse | Golgi apparatus | cell projection | postsynaptic membrane | endomembrane system | postsynapse | plasma membrane | nuclear envelope | cell leading edge | endoplasmic reticulum lumen | perinuclear region of cytoplasm | rough endoplasmic reticulum lumen | anchored component of membrane | extracellular region | membrane-bounded organelle | nucleus | organelle | axon terminus | extracellular space | cell periphery | perinuclear endoplasmic reticulum | axon | membrane-enclosed lumen | neuron projection terminus | rough endoplasmic reticulum | cell surface | intracellular | cell junction | membrane | neuron projection membrane
