QuickView for ADRA1A;jsessionid=A3A1103C5D35A4CC1F20225FF9D88447;jsessionid=BFFD34A6342AA44247023C6C2E944D4F (gene)
- Gene Symbol:
- Adra1a
Rattus norvegicus - Full name:
- adrenoceptor alpha 1A
- Synonyms:
- Adra1c, alpha-1A adrenergic receptor, adrenergic alpha 1c receptor, adrenergic receptor alpha 1c subtype, adrenergic receptor, alpha 1a, adrenergic receptor, alpha 1c, adrenergic, alpha-1A-, receptor, alpha-1A adrenoceptor, alpha-1A adrenoreceptor, alpha-1C adrenergic receptor
- Genomic Location:
- Chr 15: 46173408-46263607
- Description:
-
binds adrenergic compounds and analogs; activates phospholipase C mediated signal transduction
- Orthologs:
- Homo sapiens , Mus musculus , C. elegans , Macaca mulatta , Bos taurus , Canis lupus familiaris , Gallus gallus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , NFE2_01 , COUP_01 , AP1_C , MEF2_02 , CHX10_01 , CTCNANGTGNY_UNKNOWN , BACH2_01 , BACH1_01 , AP1_01
GO Molecular Function
alpha-adrenergic receptor activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | G-protein coupled amine receptor activity | adrenergic receptor activity | signaling receptor activity | protein heterodimerization activity | protein binding | protein dimerization activity | alpha1-adrenergic receptor activity
GO Biological Process
positive regulation of heart contraction | regulation of ERK1 and ERK2 cascade | positive regulation of action potential | regulation of blood vessel diameter | regulation of muscle system process | reflex | positive regulation of blood circulation | muscle tissue development | intracellular signal transduction | cytosolic calcium ion transport | regulation of the force of heart contraction by chemical signal | positive regulation of peptidyl-tyrosine phosphorylation | establishment of localization | regulation of autophagy | response to hormone | cell growth involved in cardiac muscle cell development | negative regulation of cellular process | cell differentiation | regulation of systemic arterial blood pressure by norepinephrine-epinephrine | striated muscle cell development | regulation of smooth muscle contraction | response to drug | organ growth | cellular chemical homeostasis | positive regulation of phosphate metabolic process | negative regulation of heart rate | cardiac cell development | cellular process | localization | cellular homeostasis | pilomotor reflex | positive regulation of synaptic transmission | positive regulation of non-membrane spanning protein tyrosine kinase activity | negative regulation of signaling | metal ion transport | developmental growth | positive regulation of protein kinase activity | alpha-adrenergic receptor activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | activation of phospholipase C activity | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | positive regulation of cardiac muscle hypertrophy | muscle structure development | muscle cell differentiation | positive regulation of vasoconstriction | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | neurological system process involved in regulation of systemic arterial blood pressure | positive regulation of cellular protein metabolic process | regulation of systemic arterial blood pressure mediated by a chemical signal | calcium ion homeostasis | G-protein coupled receptor activity | calcium ion transport into cytosol | response to stimulus | positive regulation of blood pressure | muscle cell development | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | positive regulation of protein kinase C signaling | regulation of blood vessel size | response to cocaine | adenylate cyclase-activating adrenergic receptor signaling pathway | regulation of blood circulation | cardiac muscle tissue development | G-protein coupled amine receptor activity | physiological cardiac muscle hypertrophy | regulation of heart rate | cellular localization | divalent metal ion transport | positive regulation of lipase activity | positive regulation of the force of heart contraction by chemical signal | blood circulation | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | regulation of systemic arterial blood pressure by baroreceptor feedback | modulation of chemical synaptic transmission | heart growth | metal ion homeostasis | negative regulation of blood pressure | negative regulation of blood vessel diameter | regulation of membrane potential | positive regulation of phospholipase C activity | response to nitrogen compound | regulation of protein tyrosine kinase activity | system development | adrenergic receptor activity | regulation of signal transduction | multicellular organism development | regulation of synaptic transmission, GABAergic | regulation of MAPK cascade | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of muscle contraction | regulation of catalytic activity | regulation of phosphorylation | regulation of small GTPase mediated signal transduction | nervous system process | regulation of blood pressure | excretion | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | response to ammonium ion | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | cardiocyte differentiation | regulation of the force of heart contraction | positive regulation of hydrolase activity | second-messenger-mediated signaling | regulation of Rho protein signal transduction | cardiac muscle hypertrophy | regulation of cellular protein metabolic process | cardiac muscle cell development | vasoconstriction | regulation of phospholipase activity | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure | response to xenobiotic stimulus | regulation of heart contraction | cation homeostasis | negative regulation of autophagy | regulation of striated muscle contraction | striated muscle tissue development | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of smooth muscle contraction | cyclic-nucleotide-mediated signaling | regulation of cardiac muscle contraction | regulation of protein kinase C signaling | regulation of protein metabolic process | positive regulation of signal transduction | heart development | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | positive regulation of synaptic transmission, GABAergic | regulation of tube size | positive regulation of the force of heart contraction by epinephrine-norepinephrine | negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure | striated muscle cell differentiation | positive regulation of systemic arterial blood pressure | cardiac muscle tissue growth | regulation of phospholipase C activity | positive regulation of molecular function | positive regulation of heart rate | regulation of cardiac muscle hypertrophy | positive regulation of protein modification process | response to organic substance | cAMP-mediated signaling | regulation of kinase activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | positive regulation of cardiac muscle contraction | regulation of vasoconstriction | regulation of tube diameter | positive regulation of striated muscle contraction | negative regulation of heart contraction | chemical homeostasis | calcium ion transport | negative regulation of Rho protein signal transduction | positive regulation of muscle contraction | animal organ development | negative regulation of small GTPase mediated signal transduction | negative regulation of Ras protein signal transduction | positive regulation of ERK1 and ERK2 cascade | positive regulation of kinase activity | micturition | ion homeostasis | regulation of phosphate metabolic process | response to alkaloid | phospholipase C-activating G-protein coupled receptor signaling pathway | renal system process | positive regulation of phospholipase activity | positive regulation of MAPK cascade | alpha1-adrenergic receptor activity | regulation of action potential | cardiac muscle cell differentiation | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of signal transduction | signaling | response to organic cyclic compound | negative regulation of systemic arterial blood pressure | cell development | positive regulation of phosphorylation | positive regulation of protein tyrosine kinase activity | regulation of Ras protein signal transduction | cation transport | developmental process | positive regulation of heart rate by epinephrine-norepinephrine | adrenergic receptor signaling pathway | developmental cell growth | response to organonitrogen compound | cellular metal ion homeostasis | response to anesthetic | positive regulation of metabolic process | ion transport | adult heart development | circulatory system development | aging | muscle hypertrophy | divalent inorganic cation homeostasis | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
supramolecular fiber | integral component of membrane | intracellular membrane-bounded organelle | sarcolemma | organelle membrane | sarcomere | nuclear membrane | cell | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | membrane microdomain | contractile fiber | endomembrane system | plasma membrane | nuclear envelope | membrane raft | integral component of plasma membrane | T-tubule | membrane-bounded organelle | nucleus | organelle | I band | cell periphery | plasma membrane raft | Z disc | intracellular | caveola | membrane | supramolecular complex | intrinsic component of plasma membrane
