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QuickView for ALK4;jsessionid=DA7E502F2D2A44D97B715E95A150D693;jsessionid=C9C90B117DFDC2BEE55D9AD4604DD308 (gene)


Gene Symbol:
Acvr1b Rattus norvegicus Rattus norvegicus
Full name:
activin A receptor type 1B
Synonyms:
Skr2, activin receptor type-1B, ACTR-IB, ALK-4, Serine/threonine-protein kinase receptor R2, activin A receptor, type IB, activin receptor type IB, activin receptor-like kinase 4
Genomic Location:
Chr 7: 139939001-139958740
Description:
may form a heteromeric receptor complex with type II receptors specific for TGF-beta or activin
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):


Transcripts Names
NM_199230
XM_006242315
XM_008765678
Protein Names
P80202



GO Molecular Function

transforming growth factor beta-activated receptor activity | cation binding | transmembrane signaling receptor activity | protein-containing complex binding | ribonucleotide binding | nucleotide binding | activin-activated receptor activity | carbohydrate derivative binding | protein serine/threonine kinase activity | transforming growth factor beta receptor activity, type I | inhibin binding | growth factor binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | activin binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | activin receptor activity, type I | protein binding | transmembrane receptor protein serine/threonine kinase activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | SMAD binding | metal ion binding | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of activin receptor signaling pathway | positive regulation of erythrocyte differentiation | molting cycle | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | developmental process involved in reproduction | positive regulation of trophoblast cell migration | regulation of localization | peptidyl-amino acid modification | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | nervous system development | transforming growth factor beta-activated receptor activity | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | regulation of trophoblast cell migration | regulation of cell motility | extrinsic apoptotic signaling pathway | positive regulation of pathway-restricted SMAD protein phosphorylation | response to growth factor | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | positive regulation of activin receptor signaling pathway | tissue development | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | epithelium development | response to transforming growth factor beta | development of primary sexual characteristics | response to stimulus | peptidyl-threonine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | activin-activated receptor activity | activin receptor signaling pathway | protein serine/threonine kinase activity | programmed cell death | development of primary female sexual characteristics | transforming growth factor beta receptor activity, type I | reproduction | cell cycle G1/S phase transition | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | protein modification process | embryo development | macromolecule modification | regulation of nucleic acid-templated transcription | apoptotic process | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | negative regulation of growth | multicellular organism development | phosphorus metabolic process | regulation of phosphorylation | regulation of gene expression | cell cycle | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | protein autophosphorylation | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | regulation of cellular component movement | regulation of transcription by RNA polymerase II | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | positive regulation of cell migration | regulation of cellular protein metabolic process | phosphorylation | epidermis development | skin development | mitotic cell cycle phase transition | protein phosphorylation | phosphate-containing compound metabolic process | chordate embryonic development | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of protein metabolic process | positive regulation of signal transduction | G1/S transition of mitotic cell cycle | regulation of protein phosphorylation | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | negative regulation of cell growth | apoptotic signaling pathway | activin receptor activity, type I | cellular response to transforming growth factor beta stimulus | nodal signaling pathway | protein metabolic process | transmembrane receptor protein serine/threonine kinase activity | positive regulation of protein modification process | regulation of growth | hair cycle | response to organic substance | regulation of hemopoiesis | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | metabolic process | regulation of RNA biosynthetic process | regulation of erythrocyte differentiation | hair cycle process | protein kinase activity | organic substance metabolic process | cell death | negative regulation of gene expression | animal organ development | skin epidermis development | regulation of phosphate metabolic process | transforming growth factor beta receptor signaling pathway | regulation of cell communication | signaling | regulation of transcription, DNA-templated | positive regulation of phosphorylation | cellular protein metabolic process | regulation of developmental process | kinase activity | developmental process | regulation of cell growth | cellular protein modification process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | cell cycle phase transition | positive regulation of transcription by RNA polymerase II | central nervous system development | in utero embryonic development | positive regulation of metabolic process | cellular metabolic process | female sex differentiation | cellular response to organic substance | sex differentiation | positive regulation of cell motility | regulation of cellular component organization | positive regulation of signaling | hair follicle development | signal transduction | regulation of signaling | regulation of pathway-restricted SMAD protein phosphorylation | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | catalytic complex | protein kinase complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | receptor complex | protein-containing complex | plasma membrane | transferase complex | integral component of plasma membrane | serine/threonine protein kinase complex | activin receptor complex | cell periphery | cytosol | cell surface | intracellular | membrane | intrinsic component of plasma membrane