QuickView for ALOX5;jsessionid=AFF6120FA143E6EBD2F0BCA771726146;jsessionid=CDDDCFCCCD84BE3A0D739296A151793E (gene)
- Gene Symbol:
- Alox5
Rattus norvegicus - Full name:
- arachidonate 5-lipoxygenase
- Synonyms:
- LOX5A, arachidonate 5-lipoxygenase, 5 - Lipoxygenase, 5-LO, 5-lipoxygenase
- Genomic Location:
- Chr 4: 152610283-152657891
- Description:
-
catalyzes the conversion of arachidonate to leukotriene A4 in leukotriene metabolism
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cation binding | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | iron ion binding | catalytic activity | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | arachidonate 5-lipoxygenase activity | ion binding | protein binding | dioxygenase activity | transition metal ion binding | metal ion binding | oxidoreductase activity
GO Biological Process
response to extracellular stimulus | regulation of blood vessel diameter | response to nutrient levels | positive regulation of blood circulation | leukotriene biosynthetic process | leukotriene metabolic process | defense response | cellular process | production of molecular mediator involved in inflammatory response | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen | positive regulation of vasoconstriction | icosanoid biosynthetic process | cellular lipid metabolic process | response to stimulus | monocarboxylic acid metabolic process | regulation of blood vessel size | response to stress | regulation of blood circulation | blood circulation | cellular biosynthetic process | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen | response to oxygen levels | arachidonate 5-lipoxygenase activity | lipid metabolic process | nervous system process | small molecule metabolic process | response to nutrient | biosynthetic process | sensory perception of pain | response to hyperoxia | lipoxygenase pathway | inflammatory response | regulation of tube size | long-chain fatty acid metabolic process | carboxylic acid metabolic process | regulation of vasoconstriction | metabolic process | oxidation-reduction process | regulation of tube diameter | organic substance metabolic process | dioxygenase activity | leukotriene production involved in inflammatory response | fatty acid metabolic process | sensory perception | icosanoid metabolic process | organic acid metabolic process | acute inflammatory response | cellular metabolic process | oxidoreductase activity | arachidonic acid metabolic process | multicellular organismal process
GO Cellular Component
dendrite | intracellular membrane-bounded organelle | sarcolemma | neuron projection | somatodendritic compartment | organelle membrane | nuclear membrane | cell | nuclear lumen | cytoplasm | intracellular organelle | dendritic tree | nuclear envelope lumen | cell projection | endomembrane system | nucleoplasm | plasma membrane | nuclear envelope | membrane-bounded organelle | nucleus | organelle | cell periphery | membrane-enclosed lumen | nuclear matrix | cytosol | intracellular | membrane | nuclear periphery
