QuickView for ASIC1a;jsessionid=A07D6D9FE98B7D65D639B2E5A33C8176;jsessionid=1F45B2DAC14D7152661C2762EC188DBF (gene)

Gene Symbol:

ASIC1 Homo sapiens

Full name:

acid sensing ion channel subunit 1

Synonyms:

ACCN2, ASIC, BNaC2, acid-sensing ion channel 1, Cation channel, amiloride-sensitive, neuronal, 2, acid sensing (proton gated) ion channel 1, acid-sensing ion channel 1a protein, amiloride-sensitive cation channel 2, neuronal, brain sodium channel 2

Genomic Location:

Chr 12: 48737754-48763661

Description:

This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and developmen...

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This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NKX25_01 ,  SP1_01 ,  CMYB_01 ,  TCANNTGAY_SREBP1_01 ,  ZF5_01 ,  AAAYWAACM_HFH4_01 ,  GTACTGT_MIR101 ,  TAAYNRNNTCC_UNKNOWN ,  RYCACNNRNNRNCAG_UNKNOWN ,  CTCNANGTGNY_UNKNOWN ,  TGACCTY_ERR1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  CDPCR3HD_01 ,  PAX2_01 ,  TITF1_Q3 ,  RP58_01 ,  CAGGTG_E12_Q6 ,  CTCAGGG_MIR125B_MIR125A ,  SP1_Q4_01 ,  RRAGTTGT_UNKNOWN ,  ACCAAAG_MIR9 ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  AHR_Q5 ,  TGCCAAR_NF1_Q6 ,  SPZ1_01 ,  SP1_Q6 ,  NRF1_Q6 ,  CAGTCAC_MIR134 ,  CHX10_01 ,  YGCGYRCGC_UNKNOWN ,  CART1_01 ,  IK3_01 ,  RCGCANGCGY_NRF1_Q6 ,  LXR_Q3 ,  ZF5_B ,  FOXM1_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  AGGAAGC_MIR5163P ,  SP1_Q2_01 ,  GGGTGGRR_PAX4_03 ,  AAGCACA_MIR218

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-134 ,  Predicted Gene Targets for miR-181 ,  Predicted Gene Targets for miR-218 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-326 ,  Predicted Gene Targets for miR-338 ,  Predicted Gene Targets for miR-9 ,  Predicted Gene Targets for miR-124u ,  Predicted Gene Targets for miR-29

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Cytogenetic Map:

12q13.12

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