QuickView for AT1R;jsessionid=C27B479156595E3E9557D79BF753CF94;jsessionid=00024D1EB505B2C79A7D880491534823 (gene)
- Gene Symbol:
- Agtr1a
Rattus norvegicus - Full name:
- angiotensin II receptor, type 1a
- Synonyms:
- AT1, AT1A, AT1R, Agtr1, type-1A angiotensin II receptor, angiotensin II type-1A receptor, angiotensin receptor 1a, vascular type-1 angiotensin II receptor
- Genomic Location:
- Chr 17: 40629317-40684983
- Description:
-
receptor for and mediator of vascular remodeling effects of angiotensin II
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
protein self-association | kinase binding | peptide binding | peptide hormone binding | D1 dopamine receptor binding | protein kinase binding | transmembrane signaling receptor activity | enzyme binding | angiotensin type II receptor activity | G-protein coupled receptor activity | signaling receptor binding | bradykinin receptor binding | dopamine receptor binding | amide binding | signaling receptor activity | protein heterodimerization activity | angiotensin type I receptor activity | hormone binding | protein binding | protein dimerization activity | G-protein coupled receptor binding | angiotensin receptor activity | peptide receptor activity | G-protein coupled peptide receptor activity | G-protein alpha-subunit binding
GO Biological Process
negative regulation of smooth muscle cell apoptotic process | regulation of blood vessel diameter | regulation of systemic arterial blood pressure by hormone | cell motility | intracellular signal transduction | regulation of localization | catechol-containing compound metabolic process | regulation of programmed cell death | peptidyl-amino acid modification | establishment of localization | response to hormone | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | response to dexamethasone | positive regulation of epithelial cell proliferation | positive regulation of receptor recycling | defense response | response to drug | regulation of sprouting angiogenesis | cellular chemical homeostasis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | positive regulation of endothelial cell proliferation | positive regulation of protein secretion | regulation of lipid transport | phenol-containing compound metabolic process | regulation of neuron death | cellular process | secretion | localization | cellular homeostasis | protein transport | positive regulation of reactive oxygen species metabolic process | positive regulation of protein kinase activity | macromolecule localization | negative regulation of apoptotic process | response to corticosterone | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to peptide hormone | drinking behavior | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | regulation of cytosolic calcium ion concentration | neurological system process involved in regulation of systemic arterial blood pressure | small GTPase mediated signal transduction | regulation of renal output by angiotensin | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | regulation of systemic arterial blood pressure mediated by a chemical signal | calcium ion homeostasis | urogenital system development | renin secretion into blood stream | angiotensin type II receptor activity | G-protein coupled receptor activity | regulation of peptide secretion | regulation of vasculature development | response to stimulus | positive regulation of blood pressure | vasculature development | positive regulation of protein metabolic process | regulation of blood vessel size | response to salt stress | cellular response to xenobiotic stimulus | response to stress | renin-angiotensin regulation of aldosterone production | positive regulation of JAK-STAT cascade | regulation of cell proliferation | regulation of blood circulation | response to peptide | secretion by cell | positive regulation of superoxide anion generation | response to alcohol | positive regulation of cytokine secretion | cardiovascular system development | positive regulation of sprouting angiogenesis | regulation of cholesterol esterification | positive regulation of lipase activity | catecholamine biosynthetic process | cellular response to organic cyclic compound | regulation of protein transport | blood circulation | G-protein coupled receptor signaling pathway | protein modification process | regulation of peptide transport | cellular biosynthetic process | kidney development | regulation of morphogenesis of a branching structure | macromolecule modification | regulation of steroid metabolic process | dopamine metabolic process | cell chemotaxis | activation of protein kinase activity | phospholipase C-activating angiotensin-activated signaling pathway | metal ion homeostasis | blood vessel development | negative regulation of blood vessel diameter | positive regulation of peptide secretion | locomotion | organic hydroxy compound metabolic process | response to nitrogen compound | negative regulation of neuron apoptotic process | cellular response to hormone stimulus | regulation of superoxide metabolic process | system development | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | response to activity | cell migration | cellular response to peptide hormone stimulus | phosphorus metabolic process | regulation of catalytic activity | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of secretion | organic substance transport | response to ketone | response to lipid | nervous system process | cellular response to peptide | regulation of blood pressure | regulation of systemic arterial blood pressure by renin-angiotensin | regulation of systemic arterial blood pressure | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of STAT cascade | peptide transport | positive regulation of intracellular signal transduction | response to corticosteroid | dopamine biosynthetic process | regulation of smooth muscle cell apoptotic process | positive regulation of hydrolase activity | second-messenger-mediated signaling | positive regulation of phospholipase A2 activity | positive regulation of steroid metabolic process | biosynthetic process | response to osmotic stress | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | vasoconstriction | cellular response to glucocorticoid stimulus | regulation of blood volume by renin-angiotensin | phosphorylation | regulation of phospholipase activity | angiotensin type I receptor activity | response to xenobiotic stimulus | protein phosphorylation | cation homeostasis | cellular response to corticosteroid stimulus | phosphate-containing compound metabolic process | cellular response to angiotensin | cellular response to drug | response to estrogen | regulation of muscle cell apoptotic process | angiotensin-activated signaling pathway | peptide secretion | cellular cation homeostasis | endocrine process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of neuron apoptotic process | inflammatory response | regulation of endocrine process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cholesterol esterification | heart development | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | renal system development | regulation of tube size | positive regulation of transport | drug metabolic process | positive regulation of molecular function | calcium-mediated signaling | regulation of cytokine secretion | response to angiotensin | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | activation of Janus kinase activity | Rho protein signal transduction | regulation of pH | regulation of JAK-STAT cascade | catecholamine metabolic process | regulation of kinase activity | response to antineoplastic agent | regulation of animal organ morphogenesis | regulation of intracellular signal transduction | anatomical structure development | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | regulation of vasoconstriction | metabolic process | positive regulation of branching involved in ureteric bud morphogenesis | response to mineralocorticoid | negative regulation of programmed cell death | regulation of tube diameter | amide transport | negative regulation of muscle cell apoptotic process | chemical homeostasis | brain renin-angiotensin system | regulation of secretion | behavior | organic substance metabolic process | animal organ development | regulation of endothelial cell proliferation | regulation of protein secretion | positive regulation of kinase activity | ion homeostasis | regulation of phosphate metabolic process | angiotensin receptor activity | cellular response to steroid hormone stimulus | phospholipase C-activating G-protein coupled receptor signaling pathway | renal system process | regulation of systemic arterial blood pressure by circulatory renin-angiotensin | establishment of protein localization | positive regulation of cytokine production | positive regulation of phospholipase activity | cellular response to dexamethasone stimulus | positive regulation of protein transport | regulation of cell communication | signaling | feeding behavior | G-protein coupled peptide receptor activity | response to organic cyclic compound | protein localization | regulation of epithelial cell proliferation | positive regulation of phosphorylation | regulation of phospholipase A2 activity | cellular protein metabolic process | regulation of cytokine production | regulation of developmental process | renal system process involved in regulation of systemic arterial blood pressure | developmental process | cellular protein modification process | regulation of transport | regulation of reactive oxygen species metabolic process | regulation of receptor recycling | regulation of superoxide anion generation | Ras protein signal transduction | positive regulation of kidney development | response to organonitrogen compound | cellular metal ion homeostasis | regulation of branching involved in ureteric bud morphogenesis | regulation of lipid metabolic process | positive regulation of metabolic process | positive regulation of lipid metabolic process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | regulation of cell death | protein secretion | response to steroid hormone | negative regulation of cell death | renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure | circulatory system development | aging | positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis | chemotaxis | divalent inorganic cation homeostasis | positive regulation of angiogenesis | positive regulation of signaling | signal transduction | regulation of signaling | response to glucocorticoid | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | dendrite | intracellular membrane-bounded organelle | neuron projection | somatodendritic compartment | organelle membrane | cytoplasmic vesicle | cell | organelle outer membrane | intrinsic component of membrane | cytoplasm | intracellular organelle | dendritic tree | Golgi apparatus | cell projection | recycling endosome | endomembrane system | plasma membrane | vesicle | endosome | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | membrane-enclosed lumen | basolateral plasma membrane | outer membrane | intracellular vesicle | intracellular | membrane | vesicle lumen
