QuickView for ATF3;jsessionid=4F8F8868E27DD51A9BAD3F0430BCA422;jsessionid=BF1F0E18F4FD32F61848DCDC922B4257 (gene)
- Gene Symbol:
- Atf3
Mus musculus - Full name:
- activating transcription factor 3
- Synonyms:
- LRG-21, cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, transcription factor LRG-21
- Genomic Location:
- Chr 1: 192994175-193007212
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | identical protein binding | protein heterodimerization activity | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | protein homodimerization activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | response to extracellular stimulus | regulation of ERK1 and ERK2 cascade | negative regulation of phosphorylation | positive regulation of macromolecule biosynthetic process | response to nutrient levels | negative regulation of MAPK cascade | response to endoplasmic reticulum stress | muscle tissue development | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | glucose metabolic process | cell differentiation | cellular response to extracellular stimulus | negative regulation of protein phosphorylation | positive regulation of cellular biosynthetic process | cellular process | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | negative regulation of signaling | negative regulation of nucleic acid-templated transcription | endoplasmic reticulum unfolded protein response | cellular response to starvation | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | tissue development | muscle structure development | skeletal muscle organ development | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular response to unfolded protein | response to topologically incorrect protein | cellular aromatic compound metabolic process | cellular response to topologically incorrect protein | response to stimulus | response to stress | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | response to starvation | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | negative regulation of ERK1 and ERK2 cascade | regulation of nucleic acid-templated transcription | system development | cellular response to nutrient levels | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | multicellular organism development | regulation of MAPK cascade | regulation of phosphorylation | cellular response to amino acid starvation | regulation of gene expression | regulation of extrinsic apoptotic signaling pathway | cellular response to stress | hexose biosynthetic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | monosaccharide metabolic process | small molecule metabolic process | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | carbohydrate biosynthetic process | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | positive regulation of transcription from RNA polymerase II promoter in response to stress | carbohydrate metabolic process | regulation of apoptotic signaling pathway | striated muscle tissue development | positive regulation of extrinsic apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | DNA-binding transcription factor activity | response to organic substance | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | anatomical structure development | metabolic process | regulation of DNA-templated transcription in response to stress | regulation of RNA biosynthetic process | hexose metabolic process | negative regulation of transcription, DNA-templated | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | gluconeogenesis | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | gene expression | positive regulation of programmed cell death | regulation of phosphate metabolic process | positive regulation of TRAIL-activated apoptotic signaling pathway | transcription, DNA-templated | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of signal transduction | regulation of extrinsic apoptotic signaling pathway via death domain receptors | signaling | regulation of transcription, DNA-templated | regulation of transcription from RNA polymerase II promoter in response to stress | response to unfolded protein | cellular macromolecule biosynthetic process | developmental process | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | response to amino acid starvation | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of cell death | skeletal muscle cell differentiation | positive regulation of apoptotic signaling pathway | muscle organ development | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | intracellular organelle | protein-containing complex | CHOP-ATF3 complex | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
