QuickView for BAG1;jsessionid=15C78B3E54255B10C4E06C2E66CB9E66;jsessionid=BE6CD9FE6DC26532A00E82D85AA3F719 (gene)
- Gene Symbol:
- Bag1
Rattus norvegicus - Full name:
- Bcl2 associated athanogene 1
- Synonyms:
- Bag-1, BAG family molecular chaperone regulator 1, BCL2-associated athanogene, bcl-2-associated athanogene 1
- Genomic Location:
- Chr 5: 58329339-58342322
- Description:
-
The oncogene Bcl2 encodes a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. Studies in human and mouse suggest that the protein encoded by this gene (referred to as Bcl2-associated athanogene) binds to Bcl2 protein. It enhances the anti-apoptotic effects of Bcl2 and represents a link between growth fa...
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
enzyme binding | nucleotide binding | molecular function regulator | chaperone binding | ubiquitin-like protein ligase binding | adenyl nucleotide binding | purine nucleotide binding | organic cyclic compound binding | phosphoprotein binding | protein binding | ubiquitin protein ligase binding | enzyme regulator activity | adenyl-nucleotide exchange factor activity | ATPase regulator activity | heterocyclic compound binding | small molecule binding
GO Biological Process
negative regulation of phosphorylation | positive regulation of macromolecule biosynthetic process | regulation of neurogenesis | 'de novo' posttranslational protein folding | positive regulation of apoptotic process | regulation of cell development | protein localization to mitochondrion | regulation of programmed cell death | negative regulation of neuron death | negative regulation of cellular process | positive regulation of developmental process | response to metal ion | cell differentiation | nervous system development | response to drug | negative regulation of protein phosphorylation | neurogenesis | generation of neurons | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | localization | chaperone-mediated protein folding | macromolecule localization | negative regulation of apoptotic process | positive regulation of nitrogen compound metabolic process | response to inorganic substance | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of cellular process | positive regulation of Schwann cell differentiation | regulation of apoptotic process | regulation of metabolic process | response to stimulus | regulation of Schwann cell differentiation | programmed cell death | cellular localization | positive regulation of gliogenesis | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | molecular function regulator | regulation of nucleic acid-templated transcription | negative regulation of neuron apoptotic process | apoptotic process | response to nicotine | system development | negative regulation of phosphate metabolic process | multicellular organism development | regulation of catalytic activity | regulation of phosphorylation | regulation of gene expression | regulation of motor neuron apoptotic process | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | response to lithium ion | protein localization to organelle | positive regulation of cell differentiation | 'de novo' protein folding | regulation of cellular protein metabolic process | positive regulation of neuron death | response to toxic substance | regulation of cellular metabolic process | regulation of neuron apoptotic process | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | negative regulation of motor neuron apoptotic process | neuron differentiation | response to organic substance | positive regulation of neuron apoptotic process | anatomical structure development | positive regulation of neurogenesis | positive regulation of cell development | regulation of RNA biosynthetic process | negative regulation of programmed cell death | cellular protein localization | positive regulation of glial cell differentiation | positive regulation of cell death | protein folding | cell death | negative regulation of cellular protein metabolic process | positive regulation of programmed cell death | regulation of phosphate metabolic process | negative regulation of protein metabolic process | regulation of glial cell differentiation | regulation of gliogenesis | regulation of transcription, DNA-templated | response to organic cyclic compound | protein localization | enzyme regulator activity | cellular macromolecule localization | chaperone cofactor-dependent protein refolding | regulation of nervous system development | regulation of developmental process | developmental process | adenyl-nucleotide exchange factor activity | positive regulation of transcription, DNA-templated | ATPase regulator activity | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | regulation of cell death | negative regulation of cell death | positive regulation of gene expression | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | perinuclear region of cytoplasm | mitochondrion | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular
