QuickView for BNP;jsessionid=CD323AE29B097AD904A89278E0639BA6;jsessionid=F2418066B368CE4D6A7165B3E93F36F9 (gene)

Gene Symbol:

Nppb Mus musculus

Full name:

natriuretic peptide type B

Synonyms:

AA408272, BNF, BNP, natriuretic peptides B, brain natriuretic peptide, gamma-brain natriuretic peptide, natriuretic peptide precursor type B, type-B natriuretic factor

Genomic Location:

Chr 4: 147360006-147361307

Description:

This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this g...

View Full Description

This gene encodes a secreted protein that belongs to the family of natriuretic peptides. Its precursor protein is processed to generate the active mature peptide. The mature peptide is a cardiac hormone that plays a role in ventricular remodeling as well as blood pressure regulation. Mice lacking this gene exhibit cardiac fibrosis. In humans this gene is associated with congestive heart failure, low bone-mineral density and postmenopausal osteoporosis. Alternative splicing results in multiple transcript variants encoding different isoforms.

View Less

Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CAGNWMCNNNGAC_UNKNOWN ,  NRSF_01 ,  FREAC7_01 ,  GATA4_Q3 ,  HSF_Q6 ,  TEF1_Q6 ,  TTCYRGAA_UNKNOWN ,  TGANTCA_AP1_C ,  TGATTTRY_GFI1_01

search → result