QuickView for Bdnf;jsessionid=1F4CE06A9A474BEA099AB39D4D50675C;jsessionid=9B662FA34B3057D107DCEBD0839FD777 (gene)

Gene Symbol:

Bdnf Mus musculus

Full name:

brain derived neurotrophic factor

Synonyms:

brain-derived neurotrophic factor

Genomic Location:

Chr 2: 109514857-109567200

Description:

The protein encoded by this gene is a member of the nerve growth factor family. It is involved in the growth, differentiation and survival of specific types of developing neurons both in the central nervous system (CNS) and the peripheral nervous system. It is also involved in regulating synaptic plasticity in the CNS. Expression of a similar gene ...

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The protein encoded by this gene is a member of the nerve growth factor family. It is involved in the growth, differentiation and survival of specific types of developing neurons both in the central nervous system (CNS) and the peripheral nervous system. It is also involved in regulating synaptic plasticity in the CNS. Expression of a similar gene in human is reduced in both Alzheimer's and Huntington disease patients. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes ,  Danio rerio ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACTTT_UNKNOWN ,  SP1_01 ,  NFKAPPAB65_01 ,  NFKAPPAB_01 ,  HEN1_01 ,  EVI1_04 ,  IK2_01 ,  PBX1_01 ,  CEBPA_01 ,  CEBPB_02 ,  USF_01 ,  USF_02 ,  HNF1_01 ,  OCT1_03 ,  LYF1_01 ,  OCT1_06 ,  MYB_Q6 ,  SRF_Q6 ,  CEBP_Q2 ,  NF1_Q6 ,  ATGGYGGA_UNKNOWN ,  NFKB_Q6 ,  OCT1_Q6 ,  CEBP_C ,  GATA_C ,  GRE_C ,  NFKB_C ,  CAGNWMCNNNGAC_UNKNOWN ,  TATA_C ,  SREBP1_01 ,  STAT_01 ,  AHRARNT_01 ,  ARNT_01 ,  NGFIC_01 ,  OCT1_07 ,  GFI1_01 ,  NRSF_01 ,  RREB1_01 ,  ISRE_01 ,  MIF1_01 ,  RFX1_01 ,  TCF11_01 ,  FREAC2_01 ,  PAX8_B ,  WHN_B ,  OCT1_B ,  GATA1_05 ,  PAX4_01 ,  MSX1_01 ,  EN1_01 ,  AMEF2_Q6 ,  AREB6_04 ,  IPF1_Q4 ,  SPZ1_01 ,  AR_Q2 ,  ZIC2_01 ,  STAT5A_01 ,  STAT5B_01 ,  STAT5A_02 ,  FOXO4_01 ,  FOXO1_01 ,  FOXO4_02 ,  FOXO3_01 ,  NCX_01 ,  CTGCAGY_UNKNOWN ,  PAX2_02 ,  STAT1_02 ,  STAT1_03 ,  STAT4_01 ,  STAT5A_04 ,  STAT6_02 ,  ARNT_02 ,  AFP1_Q6 ,  CTTTAAR_UNKNOWN ,  CEBPDELTA_Q6 ,  EFC_Q6 ,  GCM_Q2 ,  HOXA4_Q2 ,  MAZ_Q6 ,  PEA3_Q6 ,  SP3_Q3 ,  TEF1_Q6 ,  USF2_Q6 ,  CEBP_Q3 ,  MYB_Q3 ,  NFKB_Q6_01 ,  AHR_Q5 ,  OCT_Q6 ,  USF_Q6_01 ,  PIT1_Q6 ,  PAX_Q6 ,  CEBP_Q2_01 ,  MYB_Q5_01 ,  MYOD_Q6_01 ,  OCT1_Q5_01 ,  SP1_Q2_01 ,  CP2_02 ,  PR_01 ,  GR_01 ,  AR_03 ,  PR_02 ,  ER_Q6_02 ,  PR_Q2 ,  PXR_Q2 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  GGGYGTGNY_UNKNOWN ,  ACATTCC_MIR1_MIR206 ,  ATGCTGC_MIR103_MIR107 ,  ACAGGGT_MIR10A_MIR10B ,  ACAACTT_MIR382 ,  GTTTGTT_MIR495 ,  TTGCCAA_MIR182 ,  CATGTAA_MIR496 ,  MYAATNNNNNNNGGC_UNKNOWN ,  RAAGNYNNCTTY_UNKNOWN ,  TACAATC_MIR508 ,  AACATTC_MIR4093P ,  RNGTGGGC_UNKNOWN ,  RRAGTTGT_UNKNOWN ,  CTCTATG_MIR368 ,  ATTACAT_MIR3803P ,  TTCCGTT_MIR191 ,  RYTAAWNNNTGAY_UNKNOWN ,  TGACATY_UNKNOWN ,  TGCGCANK_UNKNOWN ,  TNCATNTCCYR_UNKNOWN ,  WGTTNNNNNAAA_UNKNOWN ,  YAATNRNNNYNATT_UNKNOWN ,  YKACATTT_UNKNOWN ,  YNGTTNNNATT_UNKNOWN ,  TGANTCA_AP1_C ,  CAGGTA_AREB6_01 ,  TAATTA_CHX10_01 ,  CAGGTG_E12_Q6 ,  TGACCTY_ERR1_Q2 ,  RYTTCCTG_ETS2_B ,  TTGTTT_FOXO4_01 ,  RTAAACA_FREAC2_01 ,  MGGAAGTG_GABP_B ,  TGATTTRY_GFI1_01 ,  AAAYWAACM_HFH4_01 ,  RGAANNTTC_HSF1_01 ,  CTTTGT_LEF1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  GCANCTGNY_MYOD_Q6 ,  TGCCAAR_NF1_Q6 ,  TGGAAA_NFAT_Q4_01 ,  GATTGGY_NFY_Q6_01 ,  GGGCGGR_SP1_Q6 ,  TCANNTGAY_SREBP1_01 ,  TTCYNRGAA_STAT5B_01 ,  TATAAA_TATA_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-10 ,  Predicted Gene Targets for miR-103 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-191 ,  Predicted Gene Targets for miR-210 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-365 ,  Predicted Gene Targets for miR-381 ,  Predicted Gene Targets for miR-382 ,  Predicted Gene Targets for miR-147 ,  Predicted Gene Targets for miR-155 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-409-3p ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-495 ,  Predicted Gene Targets for miR-496

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