QuickView for Bub3;jsessionid=9748201F5A3832CD0855F42D1C3EF548;jsessionid=CEDF6B0BC505B0787617A1F516353F75 (gene)

Gene Symbol:

Bub3 Mus musculus

Full name:

BUB3 mitotic checkpoint protein

Synonyms:

AU019800, AU021329, AU043350, AW146323, C78067, mitotic checkpoint protein BUB3, WD repeat type I transmembrane protein A72.5, budding uninhibited by benzimidazoles 3 homolog

Genomic Location:

Chr 7: 138703905-138715412

Description:

This gene encodes a component of the mitotic spindle assembly complex. The encoded protein is involved in the regulation of chromosome segregation during oocyte meiosis. Disruption of this gene results in the accumulation of mitotic errors and is lethal in the embryonic stage. Alternative splicing results in multiple transcript variants.

This gene encodes a component of the mitotic spindle assembly complex. The encoded protein is involved in the regulation of chromosome segregation during oocyte meiosis. Disruption of this gene results in the accumulation of mitotic errors and is lethal in the embryonic stage. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAAYRNCTG_UNKNOWN ,  AACTTT_UNKNOWN ,  EVI1_04 ,  ACTAYRNNNCCCR_UNKNOWN ,  HFH1_01 ,  OCT1_02 ,  OCT1_03 ,  HNF1_C ,  HFH3_01 ,  FREAC3_01 ,  FREAC7_01 ,  HFH8_01 ,  FOXJ2_01 ,  FOXO1_01 ,  FOXO4_02 ,  FOXO3_01 ,  HTF_01 ,  TEF_Q6 ,  HNF3ALPHA_Q6 ,  TGAGATT_MIR216 ,  CAGGTCC_MIR492 ,  AAAGACA_MIR511 ,  TTTTGAG_MIR373 ,  ATTCTTT_MIR186 ,  TGCTGAY_UNKNOWN ,  TTANTCA_UNKNOWN ,  WGTTNNNNNAAA_UNKNOWN ,  WTGAAAT_UNKNOWN ,  TGANTCA_AP1_C ,  CAGGTA_AREB6_01 ,  TTGTTT_FOXO4_01 ,  RTAAACA_FREAC2_01 ,  AAAYWAACM_HFH4_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-186 ,  Predicted Gene Targets for miR-216 ,  Predicted Gene Targets for miR-30 ,  Predicted Gene Targets for miR-30-3p ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-410 ,  Predicted Gene Targets for miR-452 ,  Predicted Gene Targets for miR-544

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