QuickView for C8B;jsessionid=764D4E2FCA602C494C14E61C3EEAF907;jsessionid=789672750F3C06270D6F00AA9A7D0399 (gene)
- Gene Symbol:
- C8b
Rattus norvegicus - Full name:
- complement C8 beta chain
- Synonyms:
- complement component C8 beta chain, complement component 8 subunit beta, complement component 8, beta polypeptide, complement component 8, beta subunit
- Genomic Location:
- Chr 5: 125728606-125766093
- Description:
-
one of three subunits of the component 8 (C8) of the complement cascade for immune response; important for formation of the Membrane Attack Complex
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
protein-containing complex binding
GO Biological Process
positive regulation of immune response | adaptive immune response | complement activation | regulation of immune system process | defense response | cellular process | regulation of immune response | response to stimulus | positive regulation of immune system process | response to stress | adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains | nitrogen compound metabolic process | leukocyte mediated immunity | complement activation, alternative pathway | protein activation cascade | humoral immune response | activation of immune response | protein metabolic process | complement activation, classical pathway | metabolic process | immune response | organic substance metabolic process | humoral immune response mediated by circulating immunoglobulin | B cell mediated immunity | innate immune response | cytolysis | immunoglobulin mediated immune response | immune system process | macromolecule metabolic process
GO Cellular Component
integral component of membrane | cell | plasma membrane protein complex | intrinsic component of membrane | protein-containing complex | plasma membrane | integral component of plasma membrane | extracellular region | extracellular space | cell periphery | pore complex | membrane attack complex | membrane | intrinsic component of plasma membrane
