QuickView for CACNA1D;jsessionid=5B69627D97B56DA68E561308D913ADF6;jsessionid=949F9CD7671A88BEF80227D522D08312 (gene)

Gene Symbol:

Cacna1d Mus musculus

Full name:

calcium channel, voltage-dependent, L type, alpha 1D subunit

Synonyms:

8430418G19Rik, C79217, Cach3, Cacn4, Cacnl1a2, Cav1.3, Cchl1a, Cchl1a2, D-LTCC, voltage-dependent L-type calcium channel subunit alpha-1D, Cav1.3alpha1, alpha 1 E, calcium channel, L type, alpha-1 polypeptide, voltage-gated calcium channel subunit alpha Cav1.3

Genomic Location:

Chr 14: 30853125-31304342

Description:

This gene encodes a pore-forming subunit of the L-type, voltage-activated calcium channel family. These channels have been found to play a role in heart and smooth muscle contraction and in the transmission of auditory information. Homozygous knockout mice for this gene exhibit deafness and heart defects. These channels have also been linked to mit...

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This gene encodes a pore-forming subunit of the L-type, voltage-activated calcium channel family. These channels have been found to play a role in heart and smooth muscle contraction and in the transmission of auditory information. Homozygous knockout mice for this gene exhibit deafness and heart defects. These channels have also been linked to mitochondrial oxidative stress in a mouse model of Parkinson's disease. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Gallus gallus ,  Danio rerio ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AAANWWTGC_UNKNOWN ,  AACTTT_UNKNOWN ,  NMYC_01 ,  EVI1_03 ,  EVI1_05 ,  MZF1_01 ,  HFH1_01 ,  OCT1_02 ,  OCT1_04 ,  HSF2_01 ,  OCT1_06 ,  SP1_Q6 ,  USF_C ,  STAT_01 ,  ETS1_B ,  ETS2_B ,  PAX4_01 ,  FAC1_01 ,  STAT5A_01 ,  CTTTAAR_UNKNOWN ,  EFC_Q6 ,  CYTAGCAAY_UNKNOWN ,  TEF_Q6 ,  CACBINDINGPROTEIN_Q6 ,  HFH4_01 ,  POU1F1_Q6 ,  SREBP1_Q6 ,  SREBP_Q3 ,  EGR_Q6 ,  SP1_Q4_01 ,  SP1_Q2_01 ,  AAGCCAT_MIR135A_MIR135B ,  AGGCACT_MIR5153P ,  TCCATTKW_UNKNOWN ,  TGACATY_UNKNOWN ,  CAGGTA_AREB6_01 ,  CAGGTG_E12_Q6 ,  MGGAAGTG_GABP_B ,  RGAANNTTC_HSF1_01 ,  CACGTG_MYC_Q2 ,  TGCCAAR_NF1_Q6 ,  GGGTGGRR_PAX4_03 ,  RGAGGAARY_PU1_Q6 ,  GGGCGGR_SP1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for let-7 ,  Predicted Gene Targets for miR-135 ,  Predicted Gene Targets for miR-190 ,  Predicted Gene Targets for miR-384

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