QuickView for CACNA1D;jsessionid=5B69627D97B56DA68E561308D913ADF6;jsessionid=AE8C970267230C2767F2B81EF31D61E4 (gene)
- Gene Symbol:
- Cacna1d
Rattus norvegicus - Full name:
- calcium voltage-gated channel subunit alpha1 D
- Synonyms:
- voltage-dependent L-type calcium channel subunit alpha-1D, CaV1.3alpha1, RBD, brain class D, calcium channel alpha-1 subunit, calcium channel, L type, alpha-1 polypeptide, calcium channel, voltage-dependent, L type, alpha 1D subunit, voltage-dependent calcium channel subunit alpha1D, voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker, voltage-gated calcium channel subunit alpha Cav1.3
- Genomic Location:
- Chr 16: 5383259-5703361
- Description:
-
has high voltage L-type calcium channel activity that is sensitive to dihydropyridines
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Danio rerio , Bos taurus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AAANWWTGC_UNKNOWN , AACTTT_UNKNOWN , NMYC_01 , EVI1_03 , EVI1_05 , MZF1_01 , HFH1_01 , OCT1_02 , OCT1_04 , HSF2_01
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
high voltage-gated calcium channel activity | voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | transmembrane transporter activity | ion gated channel activity | alpha-actinin binding | voltage-gated calcium channel activity | protein domain specific binding | cytoskeletal protein binding | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | ankyrin binding | protein binding | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | voltage-gated calcium channel activity involved SA node cell action potential | inorganic cation transmembrane transporter activity | PDZ domain binding | voltage-gated channel activity | channel activity | calcium channel activity | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | actinin binding | metal ion binding | ion channel activity | substrate-specific channel activity
GO Biological Process
positive regulation of insulin secretion involved in cellular response to glucose stimulus | heart process | actin filament-based process | regulation of cellular localization | intracellular signal transduction | regulation of localization | positive regulation of DNA-binding transcription factor activity | high voltage-gated calcium channel activity | establishment of localization | membrane depolarization during action potential | voltage-gated ion channel activity | regulation of peptide hormone secretion | positive regulation of protein secretion | sensory perception of mechanical stimulus | calcium ion import | cellular process | localization | passive transmembrane transporter activity | metal ion transport | actin filament-based movement | regulation of cellular process | membrane depolarization during cardiac muscle cell action potential | regulation of metabolic process | transmembrane transporter activity | heart contraction | actin-mediated cell contraction | regulation of peptide secretion | regulation of atrial cardiac muscle cell membrane repolarization | muscle contraction | response to stimulus | ion gated channel activity | regulation of insulin secretion | regulation of blood circulation | regulation of heart rate | divalent metal ion transport | positive regulation of hormone secretion | regulation of protein transport | blood circulation | G-protein coupled receptor signaling pathway | regulation of peptide transport | cell-cell signaling | regulation of nucleic acid-templated transcription | regulation of potassium ion transmembrane transport | positive regulation of peptide secretion | regulation of membrane potential | voltage-gated calcium channel activity | system development | multicellular organism development | calcium ion transmembrane transport | learning or memory | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of insulin secretion involved in cellular response to glucose stimulus | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | SA node cell to atrial cardiac muscle cell communication | regulation of gene expression | positive regulation of secretion | nervous system process | cation transmembrane transporter activity | regulation of nitrogen compound metabolic process | cardiac muscle cell action potential involved in contraction | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | second-messenger-mediated signaling | SA node cell action potential | cognition | cell-cell signaling involved in cardiac conduction | regulation of heart contraction | regulation of potassium ion transmembrane transporter activity | cell communication | regulation of cellular metabolic process | membrane depolarization during SA node cell action potential | cardiac muscle cell contraction | sensory perception of sound | heart development | positive regulation of establishment of protein localization | regulation of RNA metabolic process | positive regulation of transport | striated muscle contraction | positive regulation of peptide hormone secretion | regulation of potassium ion transport | positive regulation of molecular function | calcium-mediated signaling | cation transmembrane transport | regulation of establishment of protein localization | regulation of heart rate by cardiac conduction | positive regulation of insulin secretion | metal ion transmembrane transporter activity | regulation of DNA-binding transcription factor activity | anatomical structure development | voltage-gated cation channel activity | regulation of RNA biosynthetic process | cell communication involved in cardiac conduction | calcium ion transport | regulation of secretion | behavior | membrane depolarization | animal organ development | positive regulation of ion transport | regulation of protein secretion | SA node cell to atrial cardiac muscle cell signaling | inorganic cation transmembrane transport | regulation of ion transmembrane transport | positive regulation of protein transport | cation channel activity | memory | sensory perception | positive regulation of CREB transcription factor activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | voltage-gated calcium channel activity involved SA node cell action potential | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | regulation of transcription, DNA-templated | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | developmental process | calcium channel activity | regulation of calcium ion transport | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | regulation of transport | cardiac muscle cell action potential | ion channel activity | ion transport | cardiac muscle contraction | regulation of protein localization | circulatory system development | aging | substrate-specific channel activity | regulation of membrane repolarization | positive regulation of calcium ion transport | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | cardiac conduction | multicellular organismal process
GO Cellular Component
supramolecular fiber | integral component of membrane | dendrite | intracellular membrane-bounded organelle | sarcolemma | apical plasma membrane | neuron projection | somatodendritic compartment | cell projection membrane | sarcomere | voltage-gated calcium channel complex | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | myofibril | cytoplasm | intracellular organelle | dendritic tree | contractile fiber | leading edge membrane | apical part of cell | protein-containing complex | cell projection | plasma membrane | cell leading edge | T-tubule | calcium channel complex | dendrite membrane | membrane-bounded organelle | nucleus | organelle | I band | cell periphery | L-type voltage-gated calcium channel complex | basolateral plasma membrane | transmembrane transporter complex | neuron projection terminus | cation channel complex | ion channel complex | Z disc | intracellular | membrane | supramolecular complex | neuron projection membrane
