Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward

QuickView for CACNA2D1;jsessionid=238B2BAC8BC98B1679672FA2387E85A1;jsessionid=E928D2B6510D15EC888F2B8474F15E76 (gene)


Gene Symbol:
Cacna2d1 Mus musculus Mus musculus
Full name:
calcium channel, voltage-dependent, alpha2/delta subunit 1
Synonyms:
Ca(v)alpha2delta1, Cacna2, Cchl2a, voltage-dependent calcium channel subunit alpha-2/delta-1, dihydropyridine-sensitive calcium channel alpha 2, voltage-gated calcium channel subunit alpha-2/delta-1
Genomic Location:
Chr 5: 15440606-15876869
Description:
This gene encodes a regulatory component of the voltage-dependent calcium channel complex. The product of this gene is a proprotein that is proteolytically processed into alpha-2 and delta subunits, which are linked by a disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Danio rerio Canis lupus familiaris Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

voltage-gated ion channel activity | cation binding | passive transmembrane transporter activity | transmembrane transporter activity | ion gated channel activity | voltage-gated calcium channel activity | cation transmembrane transporter activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | ion binding | protein binding | voltage-gated calcium channel activity involved in bundle of His cell action potential | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cation channel activity | inorganic cation transmembrane transporter activity | voltage-gated channel activity | channel activity | calcium channel activity | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | metal ion binding | ion channel activity | substrate-specific channel activity

GO Biological Process

regulation of ventricular cardiac muscle cell membrane repolarization | heart process | actin filament-based process | positive regulation of ion transmembrane transporter activity | cytosolic calcium ion transport | regulation of localization | positive regulation of voltage-gated calcium channel activity | establishment of localization | membrane depolarization during action potential | cellular chemical homeostasis | positive regulation of cation channel activity | voltage-gated ion channel activity | cellular process | localization | cellular homeostasis | passive transmembrane transporter activity | metal ion transport | calcium ion transmembrane transport via high voltage-gated calcium channel | establishment of localization in cell | actin filament-based movement | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | membrane depolarization during cardiac muscle cell action potential | regulation of cytosolic calcium ion concentration | transmembrane transporter activity | bundle of His cell action potential | heart contraction | cellular response to organonitrogen compound | actin-mediated cell contraction | calcium ion homeostasis | calcium ion transport into cytosol | muscle contraction | response to stimulus | ion gated channel activity | positive regulation of cation transmembrane transport | regulation of blood circulation | response to peptide | regulation of high voltage-gated calcium channel activity | regulation of heart rate | cellular localization | divalent metal ion transport | blood circulation | cell-cell signaling | metal ion homeostasis | regulation of membrane potential | voltage-gated calcium channel activity | response to nitrogen compound | positive regulation of calcium ion transmembrane transport | calcium ion transmembrane transport | ion transmembrane transport | cellular response to peptide | cation transmembrane transporter activity | cellular ion homeostasis | positive regulation of ion transmembrane transport | positive regulation of cytosolic calcium ion concentration | cardiac muscle cell action potential involved in contraction | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | bundle of His cell to Purkinje myocyte communication | regulation of calcium ion transmembrane transport | cell-cell signaling involved in cardiac conduction | regulation of voltage-gated calcium channel activity | regulation of heart contraction | cation homeostasis | cellular cation homeostasis | cell communication | cardiac muscle cell contraction | positive regulation of transporter activity | cellular response to amyloid-beta | cellular calcium ion homeostasis | homeostatic process | positive regulation of transport | striated muscle contraction | positive regulation of molecular function | cation transmembrane transport | regulation of heart rate by cardiac conduction | response to organic substance | voltage-gated calcium channel activity involved in bundle of His cell action potential | metal ion transmembrane transporter activity | voltage-gated cation channel activity | cell communication involved in cardiac conduction | chemical homeostasis | calcium ion transport | membrane depolarization | positive regulation of ion transport | ion homeostasis | inorganic cation transmembrane transport | regulation of ion transmembrane transport | cation channel activity | regulation of action potential | transmembrane transport | action potential | signaling | inorganic cation transmembrane transporter activity | response to amyloid-beta | positive regulation of calcium ion transmembrane transporter activity | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | voltage-gated channel activity | cation transport | channel activity | regulation of ion transport | calcium channel activity | regulation of calcium ion transport | voltage-gated calcium channel activity involved in cardiac muscle cell action potential | regulation of transport | cardiac muscle cell action potential | regulation of cation channel activity | response to organonitrogen compound | cellular metal ion homeostasis | membrane depolarization during bundle of His cell action potential | regulation of membrane repolarization during action potential | ion channel activity | regulation of calcium ion transmembrane transporter activity | ion transport | cardiac muscle contraction | cellular response to organic substance | divalent inorganic cation homeostasis | substrate-specific channel activity | regulation of membrane repolarization | positive regulation of calcium ion transport | muscle system process | cardiac conduction | positive regulation of high voltage-gated calcium channel activity | multicellular organismal process

GO Cellular Component

integral component of membrane | sarcoplasmic reticulum | intracellular membrane-bounded organelle | sarcolemma | voltage-gated calcium channel complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | protein-containing complex | endomembrane system | plasma membrane | T-tubule | calcium channel complex | membrane-bounded organelle | organelle | sarcoplasm | cell periphery | L-type voltage-gated calcium channel complex | transmembrane transporter complex | cation channel complex | ion channel complex | intracellular | membrane