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QuickView for CBX2;jsessionid=0428E447F2C73975E555AA8DD46B448A;jsessionid=957211E2338E96C3BF65A638CCC2492B (gene)


Gene Symbol:
Cbx2 Mus musculus Mus musculus
Full name:
chromobox 2
Synonyms:
M33, MOD2, pc, chromobox protein homolog 2, M33 polycomb-like protein, chromobox homolog 2, modifier 3 protein, polycomb
Genomic Location:
Chr 11: 118884343-118892584
Description:
This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in results in male-to-female gonadal sex reversal.
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:





GO Molecular Function

nucleic acid binding | methylated histone binding | chromatin binding | modification-dependent protein binding | DNA binding | organic cyclic compound binding | protein binding | histone binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | developmental process involved in reproduction | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cellular process | chromatin organization | negative regulation of nucleic acid-templated transcription | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | development of primary sexual characteristics | cellular nitrogen compound biosynthetic process | reproduction | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | reproductive process | multicellular organism development | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | developmental process | organelle organization | negative regulation of transcription by RNA polymerase II | heterocycle metabolic process | chromosome organization | cellular metabolic process | sex differentiation | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

PRC1 complex | PcG protein complex | chromosome | intracellular membrane-bounded organelle | catalytic complex | nuclear ubiquitin ligase complex | cell | nuclear lumen | intracellular organelle | ubiquitin ligase complex | euchromatin | protein-containing complex | nucleoplasm | chromatin | transferase complex | membrane-bounded organelle | heterochromatin | nucleus | organelle | membrane-enclosed lumen | intracellular